PENTAGLOBIN INJECTION 50 mg/ml

INJECTION

**Dosage instructions and method of administration** The dosage is dependent on the patient's immune status and on the severity of the disease. The following dosage suggestions may be used as reference: 1. **Neonates and infants:** 5 ml (0.25 g)/kg body weight daily on 3 consecutive days. Further infusions may be required depending on the clinical course. 2. **Children and adults:** 1. Therapy of severe bacterial infections: 5 ml (0.25 g)/kg body weight daily on 3 consecutive days. Further infusions may be required depending on the clinical course. 2. Immunoglobulin substitution in immunocompromized patients: 3 – 5 ml (0.15 – 0.25 g)/kg body weight. Repetition at weekly intervals if necessary. Pentaglobin should be infused intravenously at the following rates: in neonates and infants:1.7 ml/kg/hour by infusion pumpin children and adults:0.4 ml/kg/hour**alternatively:**the first 100 ml at 0.4 ml/kg/hourthen 0.2 ml/kg/hour continuouslyuntil 15 ml/kg is reached within 72 hours **Method of administration** Intravenous use. Pentaglobin should be brought to room or body temperature before use.