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HSA Approval

EYBELIS OPHTHALMIC SOLUTION 0.002%

SIN16150P

EYBELIS OPHTHALMIC SOLUTION 0.002%

EYBELIS OPHTHALMIC SOLUTION 0.002%

April 7, 2021

SANTEN PHARMACEUTICAL ASIA PTE. LTD.

SANTEN PHARMACEUTICAL ASIA PTE. LTD.

Regulatory Information

HSA regulatory responsibility and product classification details

Regulatory Responsibility

RegistrantSANTEN PHARMACEUTICAL ASIA PTE. LTD.
Licence HolderSANTEN PHARMACEUTICAL ASIA PTE. LTD.

Product Classification

D
Drug Type
Therapeutic
F
Forensic Class
Prescription Only
HSA Singapore Classification

Formulation Information

SOLUTION, STERILE

**Posology and method of administration** Posology The recommended dose is one drop in the affected eye(s) once daily in the evening. If a dose is missed, treatment should be continued with the next dose as planned. The dose should not exceed one drop in the affected eye(s) daily. _Paediatric population_ The safety and efficacy of omidenepag isopropyl in children and adolescents have not yet been established. No data are available. Method of administration For ocular use. Be careful not to touch the tip of the bottle to the eye directly in order to avoid the contamination of the drug. If more than one topical ophthalmic product is being used, each one should be administered at least 5 minutes apart. Benzalkonium chloride may change the colour of the contact lenses. Contact lens wearers should remove the contact lenses before using this product and put them back after 5–10 minutes.

OPHTHALMIC

Medical Information

**Therapeutic indications** Reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension

**Contraindications** Hypersensitivity to the active substance or to any of the excipients listed in ‘Description’ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_. Patients with aphakic eyes or intraocular lens (IOL) inserted eyes (see ‘Undesirable effects’ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_). Concomitant use with tafluprost (see ‘Interactions’ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

S01EX06

omidenepag

Manufacturer Information

SANTEN PHARMACEUTICAL ASIA PTE. LTD.

Santen Pharmaceutical Co., Ltd. Shiga Plant

Active Ingredients

Omidenepag isopropyl

0.02 mg/ml

Omidenepag isopropyl

Documents

Package Inserts

EYBELIS Ophthalmic Solution PI.pdf

Approved: September 30, 2022

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