FLORINEF TABLET 0.1 mg

TABLET

**RECOMMENDED DOSAGE** Dosage depends on the severity of the disease and the response of the patient. The lowest possible dose should be used to control the condition being treated, and a reduction in dosage should be made (gradually) when possible. **Adrenocorticoid Insufficiency (chronic).** In Addison’s disease, the combination of **FLORINEF** with a glucocorticoid such as hydrocortisone or cortisone provides substitution therapy approximating normal adrenal activity. The usual dose for adults, adolescents, and elderly patients is one tablet (0.1 mg) of **FLORINEF** daily – range: one tablet (0.1 mg) three times a week to two tablets (0.2 mg) daily. If treatment-associated hypertension develops, the dose should be reduced to 0.05 mg daily. **FLORINEF** is preferably administered in conjunction with cortisone (10 mg to 37.5 mg daily in divided doses) or hydrocortisone (10 mg to 30 mg daily in divided doses). **Salt-losing Adrenogenital Syndrome** The recommended dosage for treating salt-losing adrenogenital syndrome is one tablet (0.1 mg) to two tablets (0.2 mg) of **FLORINEF** daily. Pediatric and Adolescent: One half tablet (0.05 mg) to one tablet (0.1 mg) daily.