DIFFLAM SOLUTION 22.5 mg/15 ml

MOUTHWASH

**DOSAGE AND ADMINISTRATION** Difflam® should generally be used undiluted, but if stinging occurs it may be diluted with water. The solution should be expelled from the mouth after use. Uninterrupted treatment should not exceed seven days. **Dosage in Adults** When used as a gargle, the usual dose Difflam® is 15 mL (approximately one tablespoon) which should be gargled for at least 30 seconds at 1½ to 3 hourly intervals, as needed. When used as a rinse for oral lesions, the usual dose is again 15 mL (approximately one tablespoon) which should be held in the mouth and swirled around for at least 30 seconds, with repeat use every 1½ to 3 hours throughout the day. **Dosage in Children** 5–15 mL as a gargle if able to do so, or as an oral rinse. **With Impaired Renal Function** Since absorbed benzydamine and its metabolites are excreted in the urine, the possibility of systemic effects should be considered in patients with severe renal impairment. **With Impaired Liver Function** Since absorbed benzydamine is highly metabolised in the liver, possibility of systemic effects should be considered in patients with severe hepatic impairment.