ADRENALINE AGUETTANT SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 0.1 MG/ML

INJECTION, SOLUTION

**4.2. Posology and method of administration** Intravenous adrenaline should only be administered by those experienced in the use and titration of vasopressors in their normal clinical practice. **Cardiopulmonary resuscitation:** 10 ml of the 0.1 mg/mL solution (1 mg) by the intravenous or intraosseous route, repeated every 3–5 minutes until return of spontaneous circulation. **Acute anaphylaxis** Titrate using intravenous boluses of 0.5 ml 0.1 mg/mL solution (0.05 mg) according to response. ADRENALINE AGUETTANT solution for injection in pre-filled syringe 0.1 mg/mL is not recommended for intramuscular use in acute anaphylaxis. For intramuscular administration, a 1mg/ml solution should be used. **Paediatric Population:** This medicinal product is not appropriate to deliver a dose of less than 0.5 ml and should therefore not be used by the intravenous or intraosseous route, in neonates and infants with body weight less than 5 kg. _Cardiac arrest in children:_ Intravenous or intraosseous route (above 5 kg only): 0.1 ml/kg of 0.1 mg/mL solution (10 micrograms/kg) to a maximum single dose of 10 ml of 0.1 mg/mL solution (1 mg), repeated every 3–5 minutes until return of spontaneous circulation.