- Approval Id
- 90cdf914217a0e87
- Drug Name
- C-FLOX 500 TABLETS 500 MG
- Product Name
- C-FLOX 500 TABLETS 500 MG
- Approval Number
- SIN11303P
- Approval Date
- 2000-04-07
- Registrant
- APOTHECA MARKETING PTE LTD
- Licence Holder
- APOTHECA MARKETING PTE LTD
- Drug Type
- Therapeutic
- Forensic Classification
- PRESCRIPTION ONLY MEDICINES
- Dosage Form
- TABLET, FILM COATED
- Dosage
- <p><strong>Dosage and Administration:</strong><br>
In adults, depending upon the type and severity of infection, C-Flox is given in a dose range of 250 mg–750 mg, administered twice daily for the period of 5–10 days.</p>
<p><strong>Dosage and Administration in special situations:</strong><br>
In gonorrhoea, single dose of 250 mg (C-Flox-250) is given. In elderly patients no dosage adjustment is usually required. In patients with severe renal impairment (serum creatinine <20ml/minute), the usual dose may be reduced to half.</p>
- Route Of Administration
- ORAL
- Indication Info
- <p><strong>Indications:</strong><br>
C-Flox is indicated for the treatment of the following infections due to sensitive bacteria:</p>
<ol>
<li>Respiratory infections: Lobar and bronchopneumonia, acute and chronic bronchitis, acute exacerbation of cystic fibrosis, bronchiectasis, empyema.</li>
<li>Ear, nose and throat infection: Otitis media, sinusitis, mastoiditis, especially infections due to Gram-negative bacteria.</li>
<li>Intra-abdominal and biliary tract infections: Infective diarrhoea, typhoid fever, cholangitis, cholecystitis.</li>
<li>Pelvic infections: Salpingitis, endometritis, pelvic inflammatory disease.</li>
<li>Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis, epididymitis.</li>
<li>Gonorrhoea: urethral, rectal and pharyngeal</li>
<li>Bone and joint infections: Osteomyelitis, septic.</li>
<li>Skin and soft tissue infections: Infected ulcers, wounds, abscesses, cellulitis, erysipelas, infected burns.</li>
<li>Systemic infections: Septicemia, peritonitis.</li>
</ol>
- Contraindications
- <p>Under <strong>Contraindications, Warnings, Precautions:</strong><br>
A history of hypersensitivity to any of the quinolones is a contraindication to the use of C-Flox. C-Flox may cause CNS stimulation which may lead to tremor, restlessness or even seizures. So C-Flox should be used with caution in patients of epilepsy. Anaphylactic reactions have also been reported to the first dose of C-Flox.<br>
The dose of C-Flox should be approximately adjusted in patients with impaired renal function. When prolonged therapy is given, the renal, hepatic and hemopoietic function must be periodically assessed.</p>
- Atc Code
- J01MA02
- Atc Item Name
- ciprofloxacin
- Pharma Manufacturer Name
- APOTHECA MARKETING PTE LTD
- Company Detail Path
- /organization/apotheca-marketing-pte-ltd
