OCTREOSCAN FOR INJECTION

INJECTION, POWDER, FOR SOLUTION

**II. Posology and method of administration** The dose for planar scintigraphy is 110 MBq in one single intravenous injection. Careful administration is necessary to avoid paravasal deposition of activity. For single photon emission tomography the dose depends on the available equipment. In general, an activity dose of 110 to 220 MBq in one single intravenous injection should be sufficient. No special dosage regimen for elderly patients is required. There is limited experience on administrations in paediatric patients, but when the use in a child is considered to be necessary, the amount of activity administered should be reduced according to standard body weight or body surface calculations. A practical approach is to adopt the recommendations of the Paediatric Task Group, European Association of Nuclear Medicine. 3 kg = 0.122 kg = 0.5042 kg = 0.784 kg = 0.1424 kg = 0.5344 kg = 0.806 kg = 0.1926 kg = 0.5646 kg = 0.828 kg = 0.2328 kg = 0.5848 kg = 0.8510 kg = 0.2730 kg = 0.6250 kg = 0.8812 kg = 0.3232 kg = 0.6552-54 kg = 0.9014 kg = 0.3634 kg = 0.6856-58 kg = 0.9216 kg = 0.4036 kg = 0.7160-62 kg = 0.9618 kg = 0.4438 kg = 0.7364-66 kg = 0.9820 kg = 0.4640 kg = 0.7668 kg = 0.99 Scintigraphy takes place approx. 24 hours after administration. When activity in the abdomen is observed at 24 hours which cannot be interpreted with certainty as uptake in tumour or activity in bowel contents, scintigraphy should be repeated at 48 hours. In some cases, scintigraphy after 4 hours gives acceptable results. Physiologic uptake occurs in spleen, liver, kidneys and bladder. Thyroid, pituitary and intestines are visible in most patients.