- Approval Id
- bfb3ff1da829f151
- Drug Name
- HERBESSER FOR INJECTION 50 mg/ampoule
- Product Name
- HERBESSER FOR INJECTION 50 mg/ampoule
- Approval Number
- SIN06012P
- Approval Date
- 1991-06-05
- Registrant
- PHARMAFORTE SINGAPORE PTE LTD
- Licence Holder
- PHARMAFORTE SINGAPORE PTE LTD
- Drug Type
- Therapeutic
- Forensic Classification
- Prescription Only
- Dosage Form
- INJECTION, POWDER, FOR SOLUTION
- Dosage
- **DOSAGE AND ADMINISTRATION**
The drug (10 mg or 50 mg as diltiazem hydrochloride) is dissolved in at least 5 ml of physiological saline or glucose solution for injection before use and administered as follows:
- Tachyarrhythmia (supraventricular)
Usually for adults, 10 mg of diltiazem hydrochloride as a single dosage is intravenously injected slowly for about 3 minutes. The dosage may be adjusted depending on the patient's age and symptoms.
- Emergency treatment for abnormal hypertension during operation
Intravenous bolus injection:
Usually for adults, 10 mg of diltiazem hydrochloride as a single dosage is intravenously injected slowly for about one minute. The dosage may be adjusted depending on the patient's age and symptoms.
Intravenous drip infusion:
Usually for adults, 5 to 15 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion. After blood pressure is lowered to the target level, adjust the drip infusion rate while monitoring blood pressure.
- Hypertensive emergency
Usually for adults, 5 to 15 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion. After blood pressure is lowered to the target level, adjust the drip infusion rate while monitoring blood pressure.
- Unstable angina
Usually for adults, 1 to 5 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion.
The dosage should be started with a low dose and may be adjusted depending on the patient's symptoms. The maximum dosage should be 5 mcg of diltiazem hydrochloride/kg body weight per minute.
- Route Of Administration
- INTRAVENOUS
- Indication Info
- **INDICATIONS**
- Tachyarrhythmia (supraventricular)
- Emergency treatment for abnormal hypertension during operation
- Hypertensive emergency
- Unstable angina
- Contraindications
- **CONTRAINDICATIONS (HERBESSER Injection is contraindicated in the following patients.)**
1. Patients with severe hypotension or cardiogenic shock \[The symptoms may be exacerbated.\]
2. Patients with 2nd or more degree atrioventricular block or sick sinus syndrome (continuous sinus bradycardia less than 50 beats/ minute, sinus arrest, sinoatrial block, etc.) \[Excessively inhibitory effect of the drug on cardiac stimulus-formation and conduction may occur.\]
3. Patients with severe congestive heart failure \[The symptoms of heart failure may be exacerbated.\]
4. Patients with severe cardiomyopathy \[The symptoms of heart failure may be exacerbated.\]
5. Patients with a history of hypersensitivity to any of the ingredients in the drug
6. Pregnant women or women who may possibly be pregnant \[See PRECAUTIONS -Use during Pregnancy, Delivery or Lactation – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_.\]
- Atc Code
- C08DB01
- Atc Item Name
- diltiazem
- Pharma Manufacturer Name
- PHARMAFORTE SINGAPORE PTE LTD
- Company Detail Path
- /organization/pharmaforte-singapore-pte-ltd
