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HSA Approval

ANSTO - Sodium Iodide [131I] Therapy Capsules (50 to 6000 MBq)

SIN16117P

ANSTO - Sodium Iodide [131I] Therapy Capsules (50 to 6000 MBq)

ANSTO - Sodium Iodide [131I] Therapy Capsules (50 to 6000 MBq)

March 8, 2021

TRANSMEDIC PTE LTD

TRANSMEDIC PTE LTD

Regulatory Information

HSA regulatory responsibility and product classification details

Regulatory Responsibility

RegistrantTRANSMEDIC PTE LTD
Licence HolderTRANSMEDIC PTE LTD

Product Classification

D
Drug Type
Therapeutic
F
Forensic Class
Prescription Only
HSA Singapore Classification

Formulation Information

CAPSULE

**Dose and Administration** The capsules are for oral administration and the dose ranges usually employed are as follows: Thyrotoxicosis150–600 MBq Thyroid ablation800–2000 MBq Thyroid carcinoma2000–6000 MBq (in two capsules)

ORAL

Medical Information

**Indications** Sodium Iodide (131I) Therapy Capsules are indicated in the treatment of hyperthyroidism, and the detection and ablation of residual functioning thyroid tissue in differentiated thyroid carcinoma.

**Contraindications** The use of this therapeutic radiopharmaceutical is absolutely contraindicated in women who are pregnant. Women of reproductive age should have a negative pregnancy test at the time of radionuclide therapy, and should take appropriate contraceptive measures. The use of therapeutic iodine-131 is not recommended in persons with renal insufficiency, as delayed excretion will result in increased whole body radiation. This therapy is contraindicated in-patients who are being treated concurrently with thyroid hormone or antithyroid drugs, are vomiting or have diarrhoea. - **Note:** “Iodine allergy” is not a contraindication for use, because of the very small chemical amounts of iodine in therapy capsules (e.g. approx. 3 microgram in a 500 MBq capsule).

V10XA01

sodium iodide (131I)

Manufacturer Information

TRANSMEDIC PTE LTD

ANSTO

Active Ingredients

Sodium Iodide [I-131]

50 to 6000 MBq/capsule

Sodium iodide

Documents

Package Inserts

ANSTO Sodium Iodide Therapy Capsules 50 to 6000 MBq Approved PI.pdf

Approved: March 8, 2021

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ANSTO - Sodium Iodide [131I] Therapy Capsules (50 to 6000 MBq) - HSA Approval | MedPath