- Approval Id
- e1ef5698eed1679a
- Drug Name
- CRINONE PROGESTERONE VAGINAL GEL 8%
- Product Name
- CRINONE PROGESTERONE VAGINAL GEL 8%
- Approval Number
- SIN10884P
- Approval Date
- 1999-04-21
- Registrant
- MERCK PTE. LTD.
- Licence Holder
- MERCK PTE. LTD.
- Drug Type
- Therapeutic
- Forensic Classification
- Prescription Only
- Dosage Form
- GEL
- Dosage
- <p><strong>Posology and method of administration</strong><br>
Intravaginal application</p>
<ul>
<li>Treatment of infertility due to inadequate luteal phase: one application (1.125 g 8 % gel) every day, starting after documented ovulation or arbitrarily on the 18th–21st day of the cycle.</li>
<li>When used during in-vitro fertilisation, daily application of Crinone<sup>®</sup> 8 % gel should be continued for 30 days if there is laboratory evidence of pregnancy. Children: not applicable.</li>
</ul>
- Route Of Administration
- VAGINAL
- Indication Info
- <p><strong>Therapeutic Indications</strong><br>
Treatment of disorders associated with progesterone deficiency, such as:</p>
<ul>
<li>infertility due to inadequate luteal phase.</li>
<li>for use during in-vitro fertilisation, where infertility is mainly due to tubal, idiopathic or endometriosis linked sterility associated with normal ovulatory cycles.</li>
</ul>
- Contraindications
- <p><strong>Contra-indications</strong></p>
<ul>
<li>known sensitivity to Crinone<sup>®</sup> (progesterone or any of the other ingredient)</li>
<li>undiagnosed vaginal bleeding</li>
<li>known or suspected malignancy of the breast or genital organ</li>
<li>acute porphyria</li>
<li>thrombophlebitis, thromboembolic disorders, cerebral apoplexy or patients with a history of these conditions</li>
<li>missed abortion</li>
</ul>
- Atc Code
- G03DA04
- Atc Item Name
- progesterone
- Pharma Manufacturer Name
- MERCK PTE. LTD.
