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HSA Approval

INDIUM (In111) CHLORIDE INJECTION 370 MBq/ml

SIN10571P

INDIUM (In111) CHLORIDE INJECTION 370 MBq/ml

INDIUM (In111) CHLORIDE INJECTION 370 MBq/ml

December 22, 1998

QT INSTRUMENTS (S) PTE LTD

QT INSTRUMENTS (S) PTE LTD

Regulatory Information

QT INSTRUMENTS (S) PTE LTD

QT INSTRUMENTS (S) PTE LTD

Therapeutic

Prescription Only

Formulation Information

INJECTION

**4.2 Posology and method of administration** The vial contains a sterile aqueous solution for the in-vitro radiolabelling of suitable conjugated proteins such as monoclonal antibodies, which are subsequently administered intravenously. The quantity of Indium (111In) chloride required for radiolabelling and the quantity of Indium (111In)-labelled pharmaceutical that is subsequently administered will depend on the pharmaceutical being labelled and its intended use. Information on recommended dosage and administration will be provided by the manufacturer of the pharmaceutical to be radiolabelled. The activity to be administered to children may be calculated approximately by correcting on a weight, body surface area or age basis the activity to adults. For the newborn and children under about one year of age, the target organ size in relation to the whole body must also be taken into consideration.

INTRAVENOUS

Medical Information

**4.1 Therapeutic indications** This product is for diagnostic use only. Indium (In111) chloride is used as an ingredient for the radiolabelling of certain suitably derivatised proteins which are subsequently administered intravenously for a variety of investigative purposes using appropriate imaging procedures. Indium (In111) chloride is used extensively for the radiolabelling of monoclonal antibodies. The nature of the disease state to be investigated will be determined by the particular monoclonal antibody to be labelled. Indium (In111) chloride has also been used as the radiolabelling ingredient in injectable preparations such as Indium (111In)-labelled proteins.

**4.3 Contraindications** Information on contra-indications to particular Indium (111In)-labelled pharmaceuticals prepared by radiolabelling with Indium (111In) chloride will be supplied by the manufacturer of the pharmaceutical to be radiolabelled.

V09IB

铟(111In)化合物类

Manufacturer Information

QT INSTRUMENTS (S) PTE LTD

Curium Netherlands B.V.

Active Ingredients

Indium (In-111) chloride

370 MBq/ml at ART

Indium

Documents

Package Inserts

07 CON 4901 Singapore SPC 15052019_clean.doc

Approved: June 29, 2020

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