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HSA Approval

GLANATEC OPHTHALMIC SOLUTION 0.4% W/V

SIN15886P

GLANATEC OPHTHALMIC SOLUTION 0.4% W/V

GLANATEC OPHTHALMIC SOLUTION 0.4% W/V

February 18, 2020

DKSH SINGAPORE PTE. LTD.

DKSH SINGAPORE PTE. LTD.

Regulatory Information

DKSH SINGAPORE PTE. LTD.

DKSH SINGAPORE PTE. LTD.

Therapeutic

Prescription Only

Formulation Information

SOLUTION, STERILE

**4.2 Posology and method of administration** **Posology** Use in adults, including the elderly Instill one drop into the affected eye(s) twice daily. Use in paediatric population Safety in low birth weight infants, newborns, infants, and children has not been established. **Method of Administration** 1. Route of administration: Instillation only. 2. When dispensing the drug: Instruct patients on the following: 1. In the instillation, the patient should tilt the head backwards, open the affected eye, instill the drug into the conjunctival sac, close the eyelid for 1 to 5 minutes while compressing the lacrimal part, and open the eye. 2. Be careful during the instillation to avoid direct contact of the tip of the container with the eye in order to prevent contamination of the drug. 3. Instill with an interval of at least 5 minutes when using the drug in combination with other ophthalmic solutions.

OPHTHALMIC

Medical Information

**4.1 Therapeutic indications** GLANATEC is indicated to decrease elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma as adjunctive therapy in patients who are insufficiently responsive to topical beta-blockers or prostaglandin analogues, or as monotherapy in patients who are intolerant or contraindicated to other intraocular pressure lowering medications.

**4.3 Contraindications** GLANATEC is contraindicated in patients with history of hypersensitivity to any of the components of GLANATEC (see Section 6.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

pending

xpending

Manufacturer Information

DKSH SINGAPORE PTE. LTD.

Teika Pharmaceutical Co., Ltd. Shinjo Factory

Active Ingredients

Ripasudil hydrochloride hydrate 0.4896g equiv. to Ripasudil

0.4g/100ml

Ripasudil

Documents

Package Inserts

Glanatec ophthalmic solution Package Insert.pdf

Approved: February 18, 2020

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