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HSA Approval

EROGRAN FOR ORAL SUSPENSION 200 mg/5 ml

SIN08042P

EROGRAN FOR ORAL SUSPENSION 200 mg/5 ml

EROGRAN FOR ORAL SUSPENSION 200 mg/5 ml

February 23, 1995

GOLDPLUS UNIVERSAL PTE LTD

GOLDPLUS UNIVERSAL PTE LTD

Regulatory Information

GOLDPLUS UNIVERSAL PTE LTD

GOLDPLUS UNIVERSAL PTE LTD

Therapeutic

Prescription Only

Formulation Information

GRANULE, FOR SUSPENSION

**DOSAGE AND ADMINISTRATION** **Adults** - **Antibacterial** Oral, the equivalent of erythromycin 400 mg every 6 hours or 800 mg every 12 hours. - **Antibacterial (streptococcal prophylaxis)** - Continuous prophylaxis of streptococcal infections in patients with a history of rheumatic heart disease and/or chorea. - Oral, the equivalent of erythromycin 400 mg every 12 hours. - **Antiprotozoal** Oral, the equivalent of erythromycin 400 mg every 6 hours for ten to fourteen days. - **Gonorrhoea (disseminated)** Oral, the equivalent of erythromycin 800 mg every 6 hours for seven days. - **Legionaires' Disease** Oral, the equivalent of erythromycin 400 mg to 1 gram every 6 hours. - **Syphilis** Oral, the equivalent of erythromycin 800 mg every 6 hours for 15 days (early syphilis) or for 30 days (late syphilis). **Usual adult prescribing limits** Antibacterial the equivalent of erythromycin up to 4 grams daily. Note: Doses up to the equivalent of 8 grams of erythromycin daily are apparently well tolerated. **Children** - **Antibacterial** Oral, the equivalent of erythromycin 7.5 to 25 mg per kg of body weight every 6 hours or 15 to 50 mg per kg of body weight every 12 hours. - **Antiprotozoal** Oral, the equivalent of erythromycin 7.5 to 12.5 mg per kg of body weight every 6 hours for 10 to 14 days. Note: 1.17 grams of erythromycin ethylsuccinate are equivalent to approximately 1 gram of erythromycin. To reconstitute, add cooled boiled water until well dispersed, then add water to the appropriate mark. Note: The information given here is limited. For further information, consult your doctor or pharmacist.

ORAL

Medical Information

**INDICATIONS** Indicated in the treatment or prophylaxis of the following: - Upper and lower respiratory tract infections. - Skin and soft-tissue infections including erythrasma. - Genitourinary tract infections including gonorrhoea and syphilis. - Intestinal amoebiasis. - Others include bacterial endocarditis, streptococcal pharyngitis, diphtheria, Legionnaires' disease and pertussis.

**CONTRAINDICATIONS** - Avoid in patients known to be hypersensitive to erythromycins - Erythromycin is contraindicated in patients taking astemizole, terfenadine, domperidone, cisapride or pimozide - Erythromycin should not be given to patients with a history of QT prolongation (congenital or documented acquired QT prolongation) or ventricular cardiac arrhythmia, including torsades de pointes (see "Warnings and Precautions" – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_) - Erythromycin should not be given to patients with electrolyte disturbances (hypokalaemia, hypomagnesaemia due to the risk of prolongation of QT interval)

J01FA01

erythromycin

Manufacturer Information

GOLDPLUS UNIVERSAL PTE LTD

HOVID BHD

Active Ingredients

ERYTHROMYCIN ETHYLSUCCINATE EQV ERYTHROMYCIN

200 mg/5 ml

Erythromycin

Documents

Package Inserts

Erogran PI.pdf

Approved: March 4, 2021

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