ORM-12741
- Generic Name
- ORM-12741
- Drug Type
- Small Molecule
- Chemical Formula
- C18H23NO2
- CAS Number
- 610782-82-6
- Unique Ingredient Identifier
- C5D3YG7ZR8
- Background
ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Single-dose Novel Selective alpha2c Antagonist Pharmaco-MRI Study in Healthy Volunteers
- First Posted Date
- 2018-02-20
- Last Posted Date
- 2019-01-10
- Lead Sponsor
- University of Cape Town
- Target Recruit Count
- 68
- Registration Number
- NCT03440021
- Locations
- 🇿🇦
UCT Dept. Psychiatry & Mental Health / CUBIC, Cape Town, Western Cape, South Africa
Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease
- First Posted Date
- 2015-06-15
- Last Posted Date
- 2018-02-15
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 308
- Registration Number
- NCT02471196
- Locations
- 🇫🇮
Clinical Research Services Turku - CRST Oy, Turku, Finland
Pharmacokinetic Study of Single Doses of ORM-12741
Phase 1
Completed
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2014-12-18
- Last Posted Date
- 2015-05-06
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 23
- Registration Number
- NCT02319057
- Locations
- 🇫🇮
Clinical Research Services Turku, CRST, Turku, Finland
Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)
Phase 1
Completed
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2014-12-01
- Last Posted Date
- 2015-05-06
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 15
- Registration Number
- NCT02303860
- Locations
- 🇫🇮
Clinical Research Services Turku - CRST Oy, Turku, Finland
Safety and Efficacy of ORM-12741 in Patients With Alzheimer's Disease
Phase 2
Completed
- Conditions
- Alzheimer's Disease
- Interventions
- First Posted Date
- 2011-03-29
- Last Posted Date
- 2021-04-28
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 100
- Registration Number
- NCT01324518
- Locations
- 🇫🇮
Clinical Research Services Turku (CRST), Turku, Finland
Safety and Pharmacokinetic Study With Multiple Ascending Doses of ORM-12741
- First Posted Date
- 2010-02-12
- Last Posted Date
- 2010-08-16
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 49
- Registration Number
- NCT01068028
- Locations
- 🇫🇷
Forenap Pharma, Rouffach, France
Early Phase I Microdosing Study of ORM-14540 and ORM-12741
- First Posted Date
- 2009-01-28
- Last Posted Date
- 2009-10-08
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 6
- Registration Number
- NCT00831077
- Locations
- 🇫🇮
CRST, Turku, Finland
A PET Study With ORM-12741
- First Posted Date
- 2009-01-27
- Last Posted Date
- 2009-11-25
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 26
- Registration Number
- NCT00829907
- Locations
- 🇫🇮
Turku PET centre, Turku, Finland
Pharmacokinetic Study of ORM-12741 in Healthy Volunteers
- First Posted Date
- 2009-01-08
- Last Posted Date
- 2009-10-08
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 12
- Registration Number
- NCT00818740
- Locations
- 🇫🇮
CRST, Turku, Finland
Excretion Balance and Metabolism After a Single Oral Dose of 14C-Labelled ORM-12741
- First Posted Date
- 2009-01-06
- Last Posted Date
- 2009-03-16
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 6
- Registration Number
- NCT00817544
- Locations
- 🇳🇱
PRA International, AE Zuitlaren, Netherlands
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