Lindane
- Generic Name
- Lindane
- Drug Type
- Small Molecule
- Chemical Formula
- C6H6Cl6
- CAS Number
- 58-89-9
- Unique Ingredient Identifier
- 59NEE7PCAB
Overview
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical treatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment. Lindane is still allowed for pharmaceutical use until 2015.
Background
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical treatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment. Lindane is still allowed for pharmaceutical use until 2015.
Indication
For the treatment of patients infested with Sarcoptes scabiei or pediculosis capitis who have either failed to respond to adequate doses, or are intolerant of other approved therapies.
Associated Conditions
- Lice Infestations
- Pediculosis Capitis
- Scabies
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
TOPICAL | 10 mg in 1 mL | 2020/12/30 | 60432-834 | ||
TOPICAL | 10 mg in 1 mL | 2009/03/17 | 61748-400 |
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
|---|
No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
|---|
No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|---|---|---|---|---|---|---|---|---|
国药准字H44020952 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2020/02/11 | Domestic | ||
国药准字H13022117 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/09/30 | Domestic | ||
国药准字H34024092 | N/A | N/A | 1% | Chemical Drug | Approved | 2003/09/27 | Domestic | ||
国药准字H44025284 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/02/15 | Domestic | ||
国药准字H42021822 | 乳膏剂 | N/A | 10g:0.1g(1%) | Chemical Drug | Approved | 2015/08/11 | Domestic | ||
国药准字H41025599 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/08/21 | Domestic | ||
国药准字H35020038 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/06/09 | Domestic | ||
国药准字H42021319 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/05/28 | Domestic | ||
国药准字H36021034 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/12/25 | Domestic | ||
国药准字H44023092 | 乳膏剂 | N/A | 1% | Chemical Drug | Approved | 2015/08/05 | Domestic |
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
|---|---|---|---|---|---|
HK-45872 | trenton-boma ltd | Non-Poison | OTC | 2000/01/21 |
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|
No TGA products found
No TGA products found for this drug