Interferon alfa
- Generic Name
- Interferon alfa
- Brand Names
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- Drug Type
- Biotech
- Chemical Formula
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- CAS Number
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- Unique Ingredient Identifier
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- Background
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13 subtypes that are called IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21. Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.
- Indication
Investigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
- Associated Conditions
- Follicular Non-Hodgkin's Lymphoma, Hematological Malignancy, Hepatitis C Virus (HCV) Infection, Malignant Melanoma, Renal Cell Carcinoma (RCC), Viral Hepatitis B
- Associated Therapies
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