MedPath

Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB

Overview

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.

Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.

Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety disorder (GAD), fibromyalgia, premature ejaculation, migraine prophylaxis, diabetic neuropathy, and neurocardiogenic syncope.

Associated Conditions

  • Binge Eating Disorder (BED)
  • Bulimia Nervosa
  • Generalized Anxiety Disorder
  • Major Depressive Disorder (MDD)
  • Obsessive Compulsive Disorder (OCD)
  • Panic Disorder
  • Post Traumatic Stress Disorder (PTSD)
  • Premenstrual Dysphoric Disorder (PMDD)
  • Social Anxiety Disorder (SAD)

FDA Approved Products

Sertraline
Manufacturer:REMEDYREPACK INC.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2024/02/22
NDC:70518-1617
SERTRALINE HYDROCHLORIDE
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:25 mg in 1 1
Approved: 2024/01/05
NDC:71335-1078
Sertraline Hydrochloride
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:100 mg in 1 1
Approved: 2021/10/01
NDC:71335-0210
SERTRALINE HYDROCHLORIDE
Manufacturer:REMEDYREPACK INC.
Route:ORAL
Strength:25 mg in 1 1
Approved: 2024/02/22
NDC:70518-1615
Sertraline Hydrochloride
Manufacturer:Aurobindo Pharma Limited
Route:ORAL
Strength:50 mg in 1 1
Approved: 2024/02/09
NDC:65862-012

Singapore Approved Products

No Singapore products found for this drug

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