MedPath

Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB

Overview

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.

Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.

Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety disorder (GAD), fibromyalgia, premature ejaculation, migraine prophylaxis, diabetic neuropathy, and neurocardiogenic syncope.

Associated Conditions

  • Binge Eating Disorder (BED)
  • Bulimia Nervosa
  • Generalized Anxiety Disorder
  • Major Depressive Disorder (MDD)
  • Obsessive Compulsive Disorder (OCD)
  • Panic Disorder
  • Post Traumatic Stress Disorder (PTSD)
  • Premenstrual Dysphoric Disorder (PMDD)
  • Social Anxiety Disorder (SAD)

FDA Approved Products

Sertraline Hydrochloride
Manufacturer:Unit Dose Services
Route:ORAL
Strength:100 mg in 1 1
Approved: 2019/01/09
NDC:50436-0013
Sertraline Hydrochloride
Manufacturer:Unit Dose Services
Route:ORAL
Strength:25 mg in 1 1
Approved: 2019/01/09
NDC:50436-0011
Sertraline hydrochloride
Manufacturer:NCS HealthCare of KY, LLC dba Vangard Labs
Route:ORAL
Strength:25 mg in 1 1
Approved: 2023/11/07
NDC:0615-8485
Sertraline
Manufacturer:RedPharm Drug, Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2022/01/20
NDC:67296-1199
SERTRALINE HYDROCHLORIDE
Manufacturer:Life Line Home Care Services
Route:ORAL
Strength:50 mg in 1 1
Approved: 2012/03/06
NDC:75921-490

Singapore Approved Products

No Singapore products found for this drug

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