Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
- First Posted Date
- 2020-01-09
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- University of Cincinnati
- Target Recruit Count
- 150
- Registration Number
- NCT04221997
- Locations
- 🇺🇸
University of Cincinnati, Cincinnati, Ohio, United States
Predicting SSRI Efficacy in Veterans With PTSD
- Conditions
- Interventions
- First Posted Date
- 2019-12-03
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 94
- Registration Number
- NCT04183205
- Locations
- 🇺🇸
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts, United States
🇺🇸Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina, United States
Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder
- Conditions
- Interventions
- First Posted Date
- 2019-11-22
- Last Posted Date
- 2024-07-30
- Target Recruit Count
- 591
- Registration Number
- NCT04174170
- Locations
- 🇺🇸
For additional information regarding sites, contact 844-687-8522, New York, New York, United States
Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD
- Conditions
- Interventions
- First Posted Date
- 2019-10-11
- Last Posted Date
- 2024-07-25
- Target Recruit Count
- 450
- Registration Number
- NCT04124614
- Locations
- 🇺🇸
For additional information regarding sites, contact 844-687-8522, San Diego, California, United States
A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women
- Conditions
- Interventions
- First Posted Date
- 2019-09-19
- Last Posted Date
- 2021-11-10
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 80
- Registration Number
- NCT04094870
- Locations
- 🇿🇲
Kamwala District Health Centre, Lusaka, Zambia
🇿🇲University Teaching Hospital, Lusaka, Zambia
Vortioxetine vs Sertraline in Mexicans
- Conditions
- Interventions
- First Posted Date
- 2019-06-07
- Last Posted Date
- 2019-06-13
- Lead Sponsor
- Universidad Juárez Autónoma de Tabasco
- Target Recruit Count
- 21
- Registration Number
- NCT03978286
A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression
- First Posted Date
- 2019-02-25
- Last Posted Date
- 2019-11-26
- Lead Sponsor
- Janssen-Cilag International NV
- Registration Number
- NCT03852160
Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment
- Conditions
- Interventions
- First Posted Date
- 2018-12-19
- Last Posted Date
- 2023-05-19
- Target Recruit Count
- 362
- Registration Number
- NCT03779789
- Locations
- 🇮🇹
Azienda Ospedaliera Universitaria Mater Domini, Università Magna Grecia, Catanzaro, Italy
🇮🇹Sapienza Università di Roma, Dipartimento di Neurologia e Psichiatria, Roma, Italy
🇮🇹Azienda Ospedaliera Universitaria Verona, Verona, Italy
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients
- Conditions
- Interventions
- First Posted Date
- 2018-03-19
- Last Posted Date
- 2021-04-01
- Lead Sponsor
- British University In Egypt
- Target Recruit Count
- 150
- Registration Number
- NCT03469128
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.