Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB
Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...

Associated Conditions
Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
Associated Therapies
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NMDA Modulation in Major Depressive Disorder in Late- Life

First Posted Date
2018-01-30
Last Posted Date
2020-12-01
Lead Sponsor
Chang Gung Memorial Hospital
Target Recruit Count
136
Registration Number
NCT03414931
Locations
🇨🇳

China Medical University Hospital, Taichung, Taiwan

🇨🇳

Chang Gung Memorial Hospital, Kaohsiung, Taiwan

Specifying and Treating Anxiety in Autism Research

First Posted Date
2017-09-12
Last Posted Date
2023-11-29
Lead Sponsor
University of California, Davis
Target Recruit Count
68
Registration Number
NCT03279471
Locations
🇺🇸

UC Davis MIND Institute, Sacramento, California, United States

Study of the Effect of Antidepressant Drugs on Neurotrophic Factors in Patients With Depression

First Posted Date
2017-04-24
Last Posted Date
2018-07-11
Lead Sponsor
All India Institute of Medical Sciences, Bhubaneswar
Target Recruit Count
105
Registration Number
NCT03126188
Locations
🇮🇳

Dept of Psychiatry, Aiims, Bhubaneswar, Bhubaneswar, Odisha, India

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

First Posted Date
2017-01-26
Last Posted Date
2021-12-08
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
336
Registration Number
NCT03033069
Locations
🇺🇸

Investigational Site, Everett, Washington, United States

Cryptococcal Antigen Screening Plus Sertraline

First Posted Date
2016-12-23
Last Posted Date
2020-06-09
Lead Sponsor
University of Minnesota
Target Recruit Count
22
Registration Number
NCT03002012
Locations
🇺🇬

Infectious Disease Institute, Makerere University, Kampala, Uganda

CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia

First Posted Date
2016-11-04
Last Posted Date
2021-01-07
Lead Sponsor
Centre for Addiction and Mental Health
Target Recruit Count
145
Registration Number
NCT02955719
Locations
🇨🇦

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

The Therapeutic Effect of Transcranial Direct Current Stimulation on Depression in Parkinson's Disease

First Posted Date
2016-09-28
Last Posted Date
2021-10-20
Lead Sponsor
National Cheng-Kung University Hospital
Target Recruit Count
15
Registration Number
NCT02917122

Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode

First Posted Date
2016-09-28
Last Posted Date
2020-11-20
Lead Sponsor
Federal University of Rio Grande do Sul
Target Recruit Count
78
Registration Number
NCT02918097

Sertraline in Addition to Standard of Care Treatment for Coccidioidomycosis

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2016-09-20
Last Posted Date
2022-03-21
Lead Sponsor
University of California, San Francisco
Registration Number
NCT02908334

Cost- Effectiveness and Quality of Life Assessment in Major Depression Disorder

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-09-15
Last Posted Date
2020-10-14
Lead Sponsor
Federal University of Rio Grande do Sul
Target Recruit Count
68
Registration Number
NCT02901249
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