CS-2009
- Generic Name
- CS-2009
CStone Submits Clinical Trial Application for CS2009, a PD-1/VEGF/CTLA-4 Trispecific Antibody
• CStone Pharmaceuticals has submitted a clinical trial application in Australia for CS2009, a trispecific antibody targeting PD-1, VEGFA, and CTLA-4.
• CS2009's design aims to preferentially target tumor-infiltrating lymphocytes, potentially reducing systemic toxicity while maintaining efficacy in solid tumors.
• Preclinical data presented at SITC 2024 demonstrated CS2009's superior anti-tumor activity compared to other immunotherapies across various cancer types.
• A first-in-human trial is planned for early 2025 in Australia, with subsequent expansion into China and the United States.
Multispecific Antibodies Market Set to Exceed $40 Billion as Next-Generation Cancer Therapies Advance
• The multispecific antibodies market has surpassed $8.6 billion in sales as of Q3 2024, with 16 approved therapies demonstrating efficacy across oncology and other therapeutic areas.
• Bispecific antibodies currently dominate the market, while more complex trispecific and tetraspecific antibodies are emerging in early development phases with potential for enhanced therapeutic advantages.
• Over 900 multispecific antibodies are currently in clinical trials, reflecting substantial investment from pharmaceutical companies and biotechnology firms seeking to address complex diseases through multi-target approaches.
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