Sugammadex

Generic Name
Sugammadex
Brand Names
Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
Drug Type
Small Molecule
Chemical Formula
C72H112O48S8
CAS Number
343306-71-8
Unique Ingredient Identifier
361LPM2T56
Background

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...

Indication

Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.

Associated Conditions
Neuromuscular blockade caused by vecuronium bromide
Associated Therapies
-
Clinical Trials
Related News

The Role of Sugammadex in Posotoperative Urinary Retention in Patients Undergoing Pelvic Floor Reconstructive Procedures

Phase 1
Recruiting
Conditions
Postoperative Urinary Retention
Interventions
Drug: Sugammadex
First Posted Date
2022-12-27
Last Posted Date
2023-07-25
Lead Sponsor
West Virginia University
Target Recruit Count
80
Registration Number
NCT05664633
Locations
🇺🇸

West Virginia University Hospitals, Morgantown, West Virginia, United States

Sugammadex as Rescue Therapy

Phase 4
Completed
Conditions
Neuromuscular Blockade
Interventions
Drug: Placebo
Drug: Sugammadex
First Posted Date
2022-12-22
Last Posted Date
2024-08-16
Lead Sponsor
Emory University
Target Recruit Count
71
Registration Number
NCT05661409
Locations
🇺🇸

Grady Memorial Hospital, Atlanta, Georgia, United States

Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular Block

First Posted Date
2022-09-19
Last Posted Date
2023-12-28
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
286
Registration Number
NCT05545280
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

Pharmacokinetics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade in Patients During Laparoscopic Surgery

Phase 4
Conditions
Pharmacokinetics
Interventions
Drug: Sugammadex
First Posted Date
2022-04-14
Last Posted Date
2022-04-14
Lead Sponsor
Guangzhou General Hospital of Guangzhou Military Command
Target Recruit Count
48
Registration Number
NCT05328778
Locations
🇨🇳

Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China

Sugammadex and Smoker's Neuromuscular Block

Phase 4
Completed
Conditions
Smoking
Neuromuscular Blockade
Interventions
Drug: sugammadex
First Posted Date
2022-04-06
Last Posted Date
2022-04-18
Lead Sponsor
Duzce University
Target Recruit Count
40
Registration Number
NCT05313100

The POUR (Postoperative Urinary Retention) Study

Phase 3
Recruiting
Conditions
Postoperative Urinary Retention
Interventions
Drug: Sugammadex
First Posted Date
2022-03-11
Last Posted Date
2024-02-28
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
140
Registration Number
NCT05276804
Locations
🇺🇸

Carolinas Medical Center, Charlotte, North Carolina, United States

Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

First Posted Date
2022-02-25
Last Posted Date
2023-09-13
Lead Sponsor
Emory University
Target Recruit Count
120
Registration Number
NCT05256901
Locations
🇺🇸

Children's Healthcare of Altanta, Atlanta, Georgia, United States

Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy

Phase 4
Conditions
Brain Tumors
Interventions
Drug: sugammadex
First Posted Date
2022-01-24
Last Posted Date
2022-03-09
Lead Sponsor
Guangzhou General Hospital of Guangzhou Military Command
Target Recruit Count
40
Registration Number
NCT05202899
Locations
🇨🇳

Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China

Pharmacokinetics of Sugammadex for the Reversal of Moderate Neuromuscular Blockade in Patients During Renal Transplantation

Phase 4
Conditions
Pharmacokinetics
Interventions
Drug: Sugammadex
First Posted Date
2022-01-11
Last Posted Date
2022-02-10
Lead Sponsor
Guangzhou General Hospital of Guangzhou Military Command
Target Recruit Count
34
Registration Number
NCT05187455
Locations
🇨🇳

Guangdong Hospital of Traditional Chinese Medicine, Guanzhou, Guangdong, China

Residual Paralysis and Reversal With Routine Neostigmine Versus Half-dose Sugammadex and Routine Neostigmine

First Posted Date
2021-10-04
Last Posted Date
2021-10-04
Lead Sponsor
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Target Recruit Count
113
Registration Number
NCT05066035
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