Sugammadex
- Generic Name
- Sugammadex
- Brand Names
- Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
- Drug Type
- Small Molecule
- Chemical Formula
- C72H112O48S8
- CAS Number
- 343306-71-8
- Unique Ingredient Identifier
- 361LPM2T56
- Background
Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...
- Indication
Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.
- Associated Conditions
- Neuromuscular blockade caused by vecuronium bromide
- Associated Therapies
- -
Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex
- Conditions
- Interventions
- First Posted Date
- 2021-08-31
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Wuhan Union Hospital, China
- Target Recruit Count
- 99
- Registration Number
- NCT05028088
- Locations
- 🇨🇳
Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China
The Feasibility of Sugammadex for General Anesthesia in Patients Undergoing Kidney and Pancreas Transplantation Surgery
- First Posted Date
- 2021-06-29
- Last Posted Date
- 2021-06-29
- Target Recruit Count
- 52
- Registration Number
- NCT04944303
- Locations
- 🇨🇳
The Second Affiliated Hospital,Guangzhou Medical University, Guangzhou, Guangdong, China
🇨🇳Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
Reversal of Neuromuscular Blockade and Perioperative Arrhythmias
- Conditions
- Interventions
- First Posted Date
- 2021-01-22
- Last Posted Date
- 2021-01-22
- Lead Sponsor
- Başakşehir Çam & Sakura City Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT04720573
- Locations
- 🇹🇷
Istanbul Medipol University, Istanbul, Turkey
Effect of Muscle Relaxation Reversal on the Success Rate of Motor Evoked Potential Recording
- Conditions
- Interventions
- First Posted Date
- 2020-10-29
- Last Posted Date
- 2022-09-21
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 170
- Registration Number
- NCT04608682
- Locations
- 🇨🇳
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China
Comparison of Time to Extubation Using Sugammadex or Neostigmine
- Conditions
- Interventions
- First Posted Date
- 2020-10-28
- Last Posted Date
- 2024-03-13
- Lead Sponsor
- Temple University
- Target Recruit Count
- 58
- Registration Number
- NCT04606901
- Locations
- 🇺🇸
Temple University Hospital, Philadelphia, Pennsylvania, United States
Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
- First Posted Date
- 2020-09-30
- Last Posted Date
- 2024-04-15
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 90
- Registration Number
- NCT04570150
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
- First Posted Date
- 2020-09-28
- Last Posted Date
- 2020-09-28
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 60
- Registration Number
- NCT04566796
- Locations
- 🇪🇬
Alexandria university, Alexandria, Egypt
A Pharmacokinetic Study of Sugammadex in Dialysis Patients
- First Posted Date
- 2020-09-21
- Last Posted Date
- 2021-09-17
- Lead Sponsor
- Tetsuro Sakai
- Registration Number
- NCT04556721
- Locations
- 🇺🇸
UPMC Montefiore Hospital, Pittsburgh, Pennsylvania, United States
Sugammadex To IMprove Bowel Function
- Conditions
- Interventions
- First Posted Date
- 2020-09-14
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Oregon Health and Science University
- Target Recruit Count
- 120
- Registration Number
- NCT04546672
- Locations
- 🇺🇸
Oregon Health & Science University, Portland, Oregon, United States
Comparison of the Impacts of Sugammadex With Neostigmine on Patency of Laryngeal Opening (Glottic Aperture Angle)
- Conditions
- Interventions
- First Posted Date
- 2020-09-10
- Last Posted Date
- 2020-09-10
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 84
- Registration Number
- NCT04545099
Drug Development Updates
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