Sugammadex
- Generic Name
- Sugammadex
- Brand Names
- Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
- Drug Type
- Small Molecule
- Chemical Formula
- C72H112O48S8
- CAS Number
- 343306-71-8
- Unique Ingredient Identifier
- 361LPM2T56
- Background
Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...
- Indication
Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.
- Associated Conditions
- Neuromuscular blockade caused by vecuronium bromide
- Associated Therapies
- -
The Use of Sugammadex in the Critically Ill
- Conditions
- Interventions
- First Posted Date
- 2019-01-03
- Last Posted Date
- 2019-08-21
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 50
- Registration Number
- NCT03791801
- Locations
- 🇨🇦
McGill University Health Center, Montreal, Quebec, Canada
🇨🇦MUHC, Montréal, Quebec, Canada
the Efficacy and Safety of Sugammadex in Children 0-2 Years Old
- Conditions
- Interventions
- First Posted Date
- 2018-11-02
- Last Posted Date
- 2018-11-02
- Target Recruit Count
- 62
- Registration Number
- NCT03728543
- Locations
- 🇷🇺
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
Reversal of Residual Neuromuscular Blockade at Train-of-four Ratio 0.3 With Sugammadex and Neostigmine
- Conditions
- Interventions
- First Posted Date
- 2018-09-04
- Last Posted Date
- 2020-08-11
- Target Recruit Count
- 121
- Registration Number
- NCT03656614
- Locations
- 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China
The Effect of Sugammadex on the Outcome After Colorectal Cancer Surgery
- First Posted Date
- 2018-08-08
- Last Posted Date
- 2019-08-20
- Lead Sponsor
- Ajou University School of Medicine
- Target Recruit Count
- 585
- Registration Number
- NCT03619759
- Locations
- 🇰🇷
Ajou university school of medicine, Suwon, Gyeonggi-do, Korea, Republic of
Residual Neuromuscular Blockade in Cardiac Surgery Patients
- Conditions
- Interventions
- First Posted Date
- 2018-07-02
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Henry Ford Health System
- Registration Number
- NCT03574337
- Locations
- 🇺🇸
Henry Ford Health Systems, Detroit, Michigan, United States
Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).
- Conditions
- Interventions
- First Posted Date
- 2018-05-09
- Last Posted Date
- 2019-04-02
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 99
- Registration Number
- NCT03519854
Role of Curarization During Anesthesia for Gynecologic Surgical Laparoscopic Procedures
- First Posted Date
- 2018-05-09
- Last Posted Date
- 2018-07-10
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 100
- Registration Number
- NCT03519633
- Locations
- 🇮🇹
Campus Bio-medico, Roma, RM, Italy
Role of Curarization During Anesthesia for Gynecologic Surgical Laparotomy Procedures
- First Posted Date
- 2018-05-09
- Last Posted Date
- 2018-07-10
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 100
- Registration Number
- NCT03519724
- Locations
- 🇮🇹
Campus Bio-medico, Roma, RM, Italy
Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
- First Posted Date
- 2018-05-01
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 7
- Registration Number
- NCT03513406
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2018-05-30
- Lead Sponsor
- The Hospital of Vestfold
- Target Recruit Count
- 144
- Registration Number
- NCT03460509
Drug Development Updates
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