MK-2206
- Generic Name
- MK-2206
- Drug Type
- Small Molecule
- Chemical Formula
- C25H21N5O
- CAS Number
- 1032349-93-1
- Unique Ingredient Identifier
- 51HZG6MP1K
Biomarker-Driven Clinical Trial Designs: Basket, Umbrella, and Platform Trials in Precision Medicine
• Basket trials leverage drug-target relationships to extend drug indications across different tumor types, identifying effective therapies based on shared molecular targets.
• Umbrella trials validate multiple therapies for a specific disease by comprehensively profiling molecular features, enabling personalized treatment strategies based on individual subtypes.
• Platform trials, as dynamic umbrella designs, efficiently screen optimal treatments in a long-term, adaptive model, ensuring patients receive the most effective interventions based on ongoing efficacy assessments.
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