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Bemiparin

Generic Name
Bemiparin
Drug Type
Small Molecule
CAS Number
91449-79-5
Unique Ingredient Identifier
PUE0TO3XDR

Overview

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and act mainly on factor-Xa, reducing the risk of bleeding due to selectivity for this specific clotting factor. Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers .

Background

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and act mainly on factor-Xa, reducing the risk of bleeding due to selectivity for this specific clotting factor. Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers .

Indication

Bemiparin is indicated in the following cases: To prevent blood clots in the veins after general abdominal surgery in patients with a moderate risk of venous thromboembolism; in the prevention of the thromboembolic disease in non-surgical patients; prevention of clotting in the extracorporeal circuit during hemodialysis; to prevent blood clots in the veins after a major orthopedic surgery in patients with high risk of venous thromboembolism; secondary prevention of venous thromboembolism; recurrence in patients with deep vein thrombosis; transient prevention and treatment of deep vein thrombosis (DVT) .

Associated Conditions

  • Extracorporeal Clotting During Hemodialysis
  • Thromboembolism

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

HIBOR SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES 2,500 IU ANTI-XA/0.2 ML
Manufacturer:ROVI PHARMA INDUSTRIAL SERVICES, S.A.
Form:INJECTION, SOLUTION
Strength:2,500 IU Anti-Xa/0.2 ml
Online:Yes
Approved: 2022/04/01
Approval:SIN16463P
HIBOR SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES 3,500 IU ANTI-XA/0.2 ML
Manufacturer:ROVI PHARMA INDUSTRIAL SERVICES, S.A.
Form:INJECTION, SOLUTION
Strength:3,500 IU Anti-Xa/0.2 ml
Online:Yes
Approved: 2022/04/01
Approval:SIN16462P

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