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Pazopanib

Generic Name
Pazopanib
Brand Names
Votrient
Drug Type
Small Molecule
Chemical Formula
C21H23N7O2S
CAS Number
444731-52-6
Unique Ingredient Identifier
7RN5DR86CK

Overview

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

Background

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

Indication

Treatment of advanced renal cell cancer and advanced soft tissue sarcoma (in patients previously treated with chemotherapy)

Associated Conditions

  • Advanced Renal Cell Carcinoma
  • Advanced Soft Tissue Sarcoma
  • Advanced Thyroid cancer

Clinical Trials

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Title
Posted
Study ID
Phase
Status
Sponsor
2014/04/15
Phase 2
Terminated
2014/03/18
Phase 2
Terminated
Interessenverband zur Qualitätssicherung der Arbeit niedergelassener Uro-Onkologen in Deutschland e.
2014/02/19
Phase 2
Completed
Grupo Espanol de Investigacion en Sarcomas
2014/02/05
Phase 1
Terminated
2014/01/07
Phase 2
Recruiting
2013/12/18
Phase 1
Completed
2013/12/12
Phase 1
Completed
2013/11/27
N/A
Completed
2013/11/15
Phase 1
Completed
2013/11/03
Phase 1
Completed
Tracon Pharmaceuticals Inc.

FDA Drug Approvals

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EMA Drug Approvals

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Status
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HSA Drug Approvals

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NMPA Drug Approvals

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PPB Drug Approvals

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TGA Drug Approvals

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