MedPath

Alefacept

Generic Name
Alefacept
Drug Type
Biotech
CAS Number
222535-22-0
Unique Ingredient Identifier
ELK3V90G6C
Background

Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.

Indication

As an immunosuppressive drug, Alefacept can be used for treatment of moderate to severe chronic plaque psoriasis

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