Oseltamivir
- Generic Name
- Oseltamivir
- Brand Names
- Ebilfumin, Tamiflu
- Drug Type
- Small Molecule
- Chemical Formula
- C16H28N2O4
- CAS Number
- 196618-13-0
- Unique Ingredient Identifier
- 20O93L6F9H
- Background
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which prevents budding f...
- Indication
According to FDA prescribing information, oseltamivir is indicated for the treatment of acute, uncomplicated illness due to influenza A and B infection in patients 2 weeks of age and older who have been symptomatic for no more than 48 hours . In particular, this agent is indicated in adults and children including full-term neonates who present with symptoms ...
- Associated Conditions
- Flu caused by Influenza, Influenza A Virus Infection, Influenza A, Influenza B, Influenza Type B
- Associated Therapies
- -
Alternative Oseltamivir Dosing Strategies
- Conditions
- First Posted Date
- 2006-06-08
- Last Posted Date
- 2017-07-02
- Target Recruit Count
- 48
- Registration Number
- NCT00334529
- Locations
- 🇺🇸
Brooke Army Medical Center, Houston, Texas, United States
🇺🇸VA Greater Los Angeles Healthcare System, Los Angeles, California, United States
🇺🇸National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Evaluation of Alternative Oseltamivir (Tamiflu) Dosing Strategies.
- First Posted Date
- 2006-03-17
- Last Posted Date
- 2009-09-23
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 48
- Registration Number
- NCT00304434
- Locations
- 🇺🇸
VA Palo Alto Health Care System, Palo Alto, California, United States
High-Dose Versus Standard-Dose Oseltamivir to Treat Severe Influenza and Avian Influenza
- First Posted Date
- 2006-03-01
- Last Posted Date
- 2014-06-06
- Target Recruit Count
- 326
- Registration Number
- NCT00298233
- Locations
- 🇸🇬
Changi General Hospital, Singapore, Singapore
🇹🇭Queen Sirikit National Institute of Child Health, Bangkok, Thailand
🇹🇭Siriraj Hospital Mahidol University, Bangkok, Thailand
Drug Development Updates
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