Niclosamide
- Generic Name
- Niclosamide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H8Cl2N2O4
- CAS Number
- 50-65-7
- Unique Ingredient Identifier
- 8KK8CQ2K8G
- Background
Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an eve...
- Indication
For the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used as a molluscicide in the control of schistosomiasis.
- Associated Conditions
- Helminthic infection, Tapeworm infestation
- Associated Therapies
- -
A Study of Niclosamide Enemas in Subjects With Active Ulcerative Proctitis or Ulcerative Proctosigmoiditis
- Conditions
- Interventions
- First Posted Date
- 2018-05-11
- Last Posted Date
- 2022-11-29
- Lead Sponsor
- Entero Therapeutics
- Target Recruit Count
- 27
- Registration Number
- NCT03521232
- Locations
- 🇮🇹
Tor Vegata, Rome, Italy
Niclosamide With Etanercept in Rheumatoid Arthritis
- Conditions
- Interventions
- First Posted Date
- 2017-05-19
- Last Posted Date
- 2018-12-12
- Lead Sponsor
- Faiq Gorial
- Target Recruit Count
- 110
- Registration Number
- NCT03160001
- Locations
- 🇮🇶
Baghdad teaching Hospital, Baghdad, Iraq
Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2017-04-21
- Last Posted Date
- 2023-04-26
- Lead Sponsor
- Mamta Parikh
- Target Recruit Count
- 6
- Registration Number
- NCT03123978
- Locations
- 🇺🇸
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2016-06-21
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Mamta Parikh
- Target Recruit Count
- 37
- Registration Number
- NCT02807805
- Locations
- 🇺🇸
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
A Study of Niclosamide in Patients With Resectable Colon Cancer
- First Posted Date
- 2016-02-22
- Last Posted Date
- 2020-02-19
- Lead Sponsor
- Michael Morse, MD
- Target Recruit Count
- 1
- Registration Number
- NCT02687009
- Locations
- 🇺🇸
Duke University, Durham, North Carolina, United States
Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer
- First Posted Date
- 2015-08-25
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 5
- Registration Number
- NCT02532114
- Locations
- 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
- First Posted Date
- 2015-08-11
- Last Posted Date
- 2018-09-12
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 37
- Registration Number
- NCT02519582
- Locations
- 🇩🇪
Charité Universitätsmedizin Berlin; Charité Comprehensive Cancer Center, Berlin, Germany
Targeted Screening for Taenia Solium Tapeworms
- Conditions
- Interventions
- First Posted Date
- 2011-02-16
- Last Posted Date
- 2014-10-24
- Lead Sponsor
- Oregon Health and Science University
- Target Recruit Count
- 1811
- Registration Number
- NCT01296958
- Locations
- 🇵🇪
San Marcos University, Lima, Peru
Mass Treatment T Solium Community Study
- Conditions
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2010-08-27
- Target Recruit Count
- 4200
- Registration Number
- NCT00138359
- Locations
- 🇵🇪
Universidad Peruana Cayetano Heredia, Lima, Peru
Drug Development Updates
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