Moclobemide

Generic Name
Moclobemide
Brand Names
Manerix
Drug Type
Small Molecule
Chemical Formula
C13H17ClN2O2
CAS Number
71320-77-9
Unique Ingredient Identifier
PJ0Y7AZB63
Background

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake in...

Indication

For the treatment of major depressive disorder and bipolar disorder .

Associated Conditions
Major Depressive Disorder (MDD)
Associated Therapies
-
Clinical Trials
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First Posted Date
2017-01-05
Last Posted Date
2019-07-24
Lead Sponsor
China Medical University Hospital
Target Recruit Count
90
Registration Number
NCT03010761

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
Drug: Phenobarbital
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Drug: Sertraline
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Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers

Phase 2
Completed
Conditions
Nicotine Dependence
Interventions
Drug: Nicotine Patch
Drug: Moclobemide
First Posted Date
2013-08-21
Last Posted Date
2017-08-23
Lead Sponsor
Jed E. Rose
Target Recruit Count
76
Registration Number
NCT01926626
Locations
🇺🇸

Duke Center for Smoking Cessation, Winston-Salem, North Carolina, United States

🇺🇸

Duke Center forSmoking Cessation, Durham, North Carolina, United States

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