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Moclobemide

Generic Name
Moclobemide
Brand Names
Manerix
Drug Type
Small Molecule
Chemical Formula
C13H17ClN2O2
CAS Number
71320-77-9
Unique Ingredient Identifier
PJ0Y7AZB63

Overview

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs). Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants .

Background

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs). Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants .

Indication

For the treatment of major depressive disorder and bipolar disorder .

Associated Conditions

  • Major Depressive Disorder (MDD)

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
MOCLOBEMIDE HEXAL TABLET 150mg
SIN13093P
TABLET
150mg
4/21/2005

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
Moclobemide Capsules
国药准字H19990322
化学药品
胶囊剂
7/14/2020
Moclobemide Tablets
国药准字H20000294
化学药品
片剂
2/8/2020
Moclobemide Tablets
国药准字H20020388
化学药品
片剂
4/19/2021
Moclobemide Tablets
国药准字H19991138
化学药品
片剂(薄膜衣)
7/2/2020
Moclobemide Tablets
国药准字H20010093
化学药品
片剂
5/11/2024
Moclobemide Tablets
国药准字H20030145
化学药品
片剂
2/6/2020

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.
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