Testosterone

Generic Name
Testosterone
Brand Names
Androderm, Androgel, Axiron, Fortesta, Natesto, Striant, Testim, Testopel, Vogelxo
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
58-22-0
Unique Ingredient Identifier
3XMK78S47O
Background

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

Testosterone was isolated from samples and also synthesized in 1935.

Indication

Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

Associated Conditions
Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer
Associated Therapies
-

The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)

First Posted Date
2011-07-01
Last Posted Date
2015-09-23
Lead Sponsor
Repros Therapeutics Inc.
Target Recruit Count
60
Registration Number
NCT01386606
Locations
🇺🇸

Cetero Research, San Antonio, Texas, United States

🇺🇸

Centex Research, Houston, Texas, United States

Antral Follicle Priming Prior to ICSI (Intracytoplasmic Sperm Injection) in Previously Diagnosed Low Responders

First Posted Date
2011-03-08
Last Posted Date
2014-02-28
Lead Sponsor
Instituto de Investigacion Sanitaria La Fe
Target Recruit Count
66
Registration Number
NCT01310647
Locations
🇪🇸

La Fe University Hospital. Department of Obstetrics and Gynecology, Valencia, Spain

Metabolic Syndrome Criteria and the Effect of Testosterone Treatment in Young Men With Hypogonadism

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-07-12
Last Posted Date
2010-07-12
Lead Sponsor
Gulhane School of Medicine
Target Recruit Count
312
Registration Number
NCT01160341
Locations
🇹🇷

Gulhane School of Medicine, Ankara, Turkey

Influence of Male Hormones on Regional Fat Metabolism

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-07-12
Last Posted Date
2014-05-14
Lead Sponsor
Mayo Clinic
Target Recruit Count
39
Registration Number
NCT01160328
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Hypogonadism in Young Men With Type 2 Diabetes

First Posted Date
2010-07-01
Last Posted Date
2019-10-04
Lead Sponsor
State University of New York at Buffalo
Target Recruit Count
5
Registration Number
NCT01155518
Locations
🇺🇸

Millard Fillmore Gates Hospital, Buffalo, New York, United States

Testosterone Replacement in Men With Diabetes and Obesity

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-05-21
Last Posted Date
2022-11-29
Lead Sponsor
University at Buffalo
Target Recruit Count
137
Registration Number
NCT01127659
Locations
🇺🇸

115 Flint Road, Williamsville, New York, United States

Testosterone Replacement in Metabolic Syndrome and Inflammation

First Posted Date
2010-05-14
Last Posted Date
2014-10-28
Lead Sponsor
University of Roma La Sapienza
Target Recruit Count
82
Registration Number
NCT01123278
Locations
🇮🇹

Dipartimento di Fisiopatologia Medica - Policlinico Umberto I, Rome, Italy

🇮🇹

Policlinico Umberto I Hospital - Sapienza University, Rome, Italy

Hormonal Factors in the Treatment of Anorexia Nervosa

First Posted Date
2010-05-12
Last Posted Date
2020-09-02
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
90
Registration Number
NCT01121211
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2010-03-10
Last Posted Date
2019-04-04
Lead Sponsor
Tameside Hospital NHS Foundation Trust
Target Recruit Count
22
Registration Number
NCT01084369
Locations
🇬🇧

Tameside Hospital NHS Foundatoin Trust, Ashton under Lyne, United Kingdom

🇬🇧

Tameside General Hospital, Ashton-under-Lyne, Lancashire, United Kingdom

Metabolic Effects of Steroids in Obese Men

First Posted Date
2009-09-24
Last Posted Date
2011-03-16
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
57
Registration Number
NCT00983554
Locations
🇺🇸

University of California, San Diego, San Diego, California, United States

🇺🇸

VA San Diego Healthcare System, San Diego, California, United States

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