Mexiletine
- Generic Name
- Mexiletine
- Brand Names
- Namuscla
- Drug Type
- Small Molecule
- Chemical Formula
- C11H17NO
- CAS Number
- 31828-71-4
- Unique Ingredient Identifier
- 1U511HHV4Z
- Background
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
- Indication
For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.
- Associated Conditions
- Ventricular Arrhythmia, Ventricular Tachycardia, Sustained
- Associated Therapies
- -
The Effect of Late Na Current Blocker Mexiletine on Giant T-wave Electrical Alternans(STOP-TWA)
- Conditions
- Interventions
- First Posted Date
- 2022-11-16
- Last Posted Date
- 2024-04-04
- Target Recruit Count
- 50
- Registration Number
- NCT05619120
- Locations
- 🇨🇳
First Affiliated Hospital of Xian Jiantong University, Xi'an, Shaanxi, China
MExiletine Versus Lamotrigine in Non-Dystrophic Myotonias
- Conditions
- Interventions
- First Posted Date
- 2021-08-23
- Last Posted Date
- 2022-11-02
- Lead Sponsor
- University College, London
- Target Recruit Count
- 60
- Registration Number
- NCT05017155
- Locations
- 🇬🇧
University College London Hospital, London, United Kingdom
Open Label Study in Adolescents and Children With Myotonic Disorders
- First Posted Date
- 2020-11-12
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- Lupin Ltd.
- Target Recruit Count
- 12
- Registration Number
- NCT04624750
- Locations
- 🇫🇷
Hôpital Necker-Enfants-Malades, Paris, France
Open-label Extension Study in Paediatric Patients Who Have Completed the MEX-NM-301 Study.
- First Posted Date
- 2020-11-10
- Last Posted Date
- 2024-05-06
- Lead Sponsor
- Lupin Ltd.
- Target Recruit Count
- 14
- Registration Number
- NCT04622553
- Locations
- 🇫🇷
Hôpital Necker-Enfants-Malades, Paris, France
An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders
- Conditions
- First Posted Date
- 2020-11-05
- Last Posted Date
- 2024-05-06
- Lead Sponsor
- Lupin Ltd.
- Target Recruit Count
- 53
- Registration Number
- NCT04616807
- Locations
- 🇫🇷
Hôpital Universitaire de La Pitié Salpêtrière, Paris, Cedex, France
🇫🇷CHRU Lille, Lille, France
🇩🇪Universitätsklinikum Ulm, Klinik für Neurologie, Ulm, Germany
Mexiletine in Sporadic Amyotrophic Lateral Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2016-05-24
- Last Posted Date
- 2019-12-05
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 20
- Registration Number
- NCT02781454
- Locations
- 🇺🇸
Barrow Neurological Institute, Phoenix, Arizona, United States
🇺🇸University of Washington, Seattle, Washington, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease
- First Posted Date
- 2015-09-28
- Last Posted Date
- 2018-03-26
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 4
- Registration Number
- NCT02561702
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
Mexiletine and Non Dystrophic Myotonias
- Conditions
- Interventions
- First Posted Date
- 2015-01-13
- Last Posted Date
- 2015-01-13
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 24
- Registration Number
- NCT02336477
- Locations
- 🇫🇷
Groupe Hospitalier Pitié Salpetriere, Paris, France
Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
- Conditions
- Interventions
- First Posted Date
- 2014-12-04
- Last Posted Date
- 2016-06-08
- Lead Sponsor
- Food and Drug Administration (FDA)
- Target Recruit Count
- 22
- Registration Number
- NCT02308748
Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations
- Conditions
- Interventions
- First Posted Date
- 2014-10-09
- Last Posted Date
- 2018-07-06
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 402
- Registration Number
- NCT02260388
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸University of Miami Miller School of Medicine, Miami, Florida, United States
🇺🇸Indiana University, Indianapolis, Indiana, United States
Drug Development Updates
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