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N-acetyltyrosine

Generic Name
N-acetyltyrosine
Brand Names
Aminosyn II 7 %, Sulfite-free, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C11H13NO4
CAS Number
537-55-3
Unique Ingredient Identifier
DA8G610ZO5

Overview

N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. Tyrosine is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a source of nutritional support where oral nutrition is inadequate or cannot be tolerated.

Indication

N-acetyltyrosine is indicated, in combination with several other amino acids and dextrose, as a peripherally administered source of nitrogen for nutritional support in patients with adequate stores of body fat in whom, for short periods, oral administration cannot be tolerated, is undesirable, or inadequate . It is also indicated, with other amino acids, 5-10% dextrose, and fat emulsion, for parenteral nutrition to preserve protein and reduce catabolism in stress conditions where oral administration is inadequate . When administered with other amino acids and concentrated dextrose, it is indicated for central vein infusion to prevent or reverse negative nitrogen balance in patients where the alimentary tract by the oral, gastrostomy, or jejestomy routes cannot or should not be used or in patients in which gastrointestinal absorption of protein is impaired, metabolic requirements for protein are substantially increased, or morbidity and mortality may be reduced by replacing amino acids lost from tissue breakdown

Associated Conditions

No associated conditions information available.

Clinical Trials

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Posted
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No clinical trials found

No clinical trials found for this drug

FDA Drug Approvals

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No FDA approvals found for this drug.

EMA Drug Approvals

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No EMA approvals found for this drug.

HSA Drug Approvals

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No HSA approvals found for this drug.

NMPA Drug Approvals

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No NMPA approvals found for this drug.

PPB Drug Approvals

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No PPB approvals found for this drug.

TGA Drug Approvals

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No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
AMINOSYN II 8.5% WITH 50% DEXTROSE
hospira healthcare ulc
00742767
Solution - Intravenous
115 MG / 100 ML
12/31/1988
AMINOSYN II 7% WITH 10% DEXTROSE
hospira healthcare ulc
00742740
Solution - Intravenous
94 MG / 100 ML
12/31/1988
AMINOSYN II IN DEXTROSE INJECTION
hospira healthcare ulc
00839302
Solution - Intravenous
115 MG / 100 ML
12/31/1991
AMINOSYN II 8.5% INJECTION
hospira healthcare ulc
00742627
Solution - Intravenous
230 MG / 100 ML
12/31/1987
AMINOSYN II 7% INJECTION
hospira healthcare ulc
00742635
Solution - Intravenous
189 MG / 100 ML
12/31/1987
AMINOSYN II IN DEXTROSE INJECTION
hospira healthcare ulc
00742783
Solution - Intravenous
135 MG / 100 ML
12/31/1987
AMINOSYN II 5% INJ
ABBOTT LABORATORIES, LIMITED
00742643
Liquid - Intravenous
135 MG / 100 ML
12/31/1988
AMINOSYN II
ICU Medical Canada Inc
02126745
Solution - Intravenous
405 MG / 100 ML
12/31/1995
AMINOSYN II 8.5% M IN 20% DEXTROSE (DUAL CHAMBER)
hospira healthcare ulc
00742716
Solution - Intravenous
115 MG / 100 ML
12/31/1987
AMINOSYN II 10% WITH ELECTROLYTES
hospira healthcare ulc
00742651
Solution - Intravenous
270 MG / 100 ML
12/31/1991

CIMA AEMPS Drug Approvals

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Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

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No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

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No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

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No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

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No UK EMC drug information found for this drug.

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