Parathyroid hormone
- Generic Name
- Parathyroid hormone
- Brand Names
- Natpara, Natpar
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 9002-64-6
- Unique Ingredient Identifier
- N19A0T0E5J
- Background
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids polypeptide (9.4 kDa).
Preotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and is marketed in Europe by Nycomed. Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA).
- Indication
For use/treatment in osteoporosis.
- Associated Conditions
- Hypocalcemia, Hypoparathyroidism
- Associated Therapies
- -
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Drug Development Updates
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