Menthol
- Generic Name
- Menthol
- Brand Names
- Absorbine Jr Antifungal, Mentholatum
- Drug Type
- Small Molecule
- Chemical Formula
- C10H20O
- CAS Number
- 2216-51-5
- Unique Ingredient Identifier
- BZ1R15MTK7
- Background
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used to relieve minor throat irritations.
- Indication
Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
- Associated Conditions
- Allergic Reaction, Back Pain Lower Back, Back pain, Chilblains, Common Cold, Contusions, Cough, Cough caused by Common Cold, Dandruff, Flu caused by Influenza, Generalised muscle aches, Haemorrhoids, Intercostal Pain, Itching caused by Dandruff, Itching of the scalp, Joint Pain, Mild pain, Muscle Strain, Muscle; Fatigue, Myalgia, Nasal Congestion, Oral Pain, Pain caused by Fracture Bone, Productive cough, Psoriasis, Redness of the scalp, Seborrheic Dermatitis, Shoulder Stiffness, Sore Throat, Sprains, Stiff Shoulder, Stiff neck, Swelling, Upper Respiratory Tract Infection, Articular inflammation, Hematomas, Muscle, joint pains, Nonspecific pain, Scalp irritation
- Associated Therapies
- Sports Massage
Efficacy of L-menthol on Breathlessness in Chronic Obstructive Pulmonary Disease
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Interventions
- Other: Placebo
- First Posted Date
- 2023-06-05
- Last Posted Date
- 2024-07-09
- Lead Sponsor
- Region Skane
- Target Recruit Count
- 20
- Registration Number
- NCT05888597
- Locations
- 🇸🇪
Lund University, Lund, Sweden
Antiperistaltic Effect and Safety of L-menthol in the Elderly With Contraindication to Buscopan
- First Posted Date
- 2020-10-20
- Last Posted Date
- 2020-10-20
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 60
- Registration Number
- NCT04593836
- Locations
- 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan
Study of NPO-13 During Colonoscopy
- Conditions
- Bowel Disease
- First Posted Date
- 2019-09-20
- Last Posted Date
- 2020-08-17
- Lead Sponsor
- Nihon Pharmaceutical Co., Ltd
- Target Recruit Count
- 158
- Registration Number
- NCT04097574
- Locations
- 🇯🇵
NPO-13 Trial Site 12, Kurume, Fukuoka, Japan
🇯🇵NPO-13 Trial Site 1, Shimotsuke, Tochigi, Japan
🇯🇵NPO-13 Trial Site 2, Maebashi, Gunma, Japan
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
- Conditions
- PainPruritusDermatology/Skin - OtherNeuropathic Pain
- Interventions
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2017-04-27
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 22
- Registration Number
- NCT03132142
- Locations
- 🇩🇰
SMI, Aalborg, Denmark
Phase Ⅱ Dose Response Study of NPO-13 in Patients Undergoing Total Colonoscopy
- First Posted Date
- 2014-10-16
- Last Posted Date
- 2021-11-16
- Lead Sponsor
- Nihon Pharmaceutical Co., Ltd
- Target Recruit Count
- 132
- Registration Number
- NCT02265939
Drug Development Updates
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