Bisacodyl

Generic Name
Bisacodyl
Brand Names
Alophen Reformulated Jan 2008, Bi-peglyte, Bisac-evac, Carters Little Pills, Dulcolax, Fleet Mineral Oil, Gavilyte-H and Bisacodyl
Drug Type
Small Molecule
Chemical Formula
C22H19NO4
CAS Number
603-50-9
Unique Ingredient Identifier
10X0709Y6I
Background

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).

Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.

Indication

Bisacodyl is indicated to relieve occasional constipation and irregularity.

Associated Conditions
Bowel movement irregularity, Constipation, Occasional Constipation
Associated Therapies
Bowel preparation therapy

Pharmacokinetics of Bisacodyl or Sodium Picosulfate Administered Orally in Healthy Lactating Females

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-08-08
Last Posted Date
2014-08-08
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
16
Registration Number
NCT02211911

12-Week Study of Plecanatide for CIC (The CIC3 Study)

First Posted Date
2013-11-13
Last Posted Date
2019-12-26
Lead Sponsor
Bausch Health Americas, Inc.
Target Recruit Count
1394
Registration Number
NCT01982240
Locations
🇨🇦

Synergy Research Site, St-Romuald, Quebec, Canada

Effect of Octreotide on the Colonic Motility in Pediatric Patients

First Posted Date
2013-08-07
Last Posted Date
2015-12-21
Lead Sponsor
Indiana University
Target Recruit Count
13
Registration Number
NCT01917773
Locations
🇺🇸

Motility Laboratory, Division of Pediatric Gastroenterology, Hepatology and Nutrition at the James Whitcomb Riley Hospital for Children,, Indianapolis, Indiana, United States

Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-06-26
Last Posted Date
2014-06-17
Lead Sponsor
Ospedale Santa Maria delle Croci
Target Recruit Count
116
Registration Number
NCT01887158
Locations
🇮🇹

Ospedale S.Maria delle Croci, Ravenna, RA, Italy

🇮🇹

Alessandro Mussetto, Ravenna, RA, Italy

Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery

First Posted Date
2013-06-18
Last Posted Date
2013-06-18
Lead Sponsor
Oslo University Hospital
Target Recruit Count
45
Registration Number
NCT01879605
Locations
🇳🇴

Oslo Universitetssykehus, Oslo, Norway

Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients

First Posted Date
2013-05-15
Last Posted Date
2013-05-15
Lead Sponsor
Corporacion Parc Tauli
Target Recruit Count
162
Registration Number
NCT01853709
Locations
🇪🇸

Hospital de Sabadell, Sabadell, Barcelona, Spain

Improving Bowel Preparation for the Colon Capsule

First Posted Date
2012-08-01
Last Posted Date
2015-12-03
Lead Sponsor
Queen's University
Target Recruit Count
20
Registration Number
NCT01655095
Locations
🇨🇦

Hotel Dieu Hospital, Kingston, Ontario, Canada

Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep

First Posted Date
2010-02-23
Last Posted Date
2013-02-12
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
608
Registration Number
NCT01073930
Locations
🇺🇸

Louisiana Research Center LLC, Shreveport, Louisiana, United States

🇺🇸

Indiana University Hospital, Indianapolis, Indiana, United States

🇺🇸

Piedmont Medical Research Associates, Winston-Salem, North Carolina, United States

and more 6 locations

Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep

First Posted Date
2010-02-23
Last Posted Date
2012-10-30
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
603
Registration Number
NCT01073943
Locations
🇺🇸

Florida Clinical Research Group, Clearwater, Florida, United States

🇺🇸

Gastroenterology Research Consultants of Greater Cincinnati, Cincinnati, Ohio, United States

🇺🇸

Investigational site, Hollywood, Florida, United States

and more 8 locations

Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation

First Posted Date
2010-02-05
Last Posted Date
2013-11-18
Lead Sponsor
Gastroenterology Services, Ltd.
Target Recruit Count
600
Registration Number
NCT01063049
Locations
🇺🇸

Gastroenterology Services, Downers Grove, Illinois, United States

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