MedPath

EO-2463

Generic Name
EO-2463

Microbiome Therapeutics Pipeline Expands with 180+ Novel Therapies in Development Across 140 Companies

• The microbiome therapeutics landscape shows remarkable growth with over 140 companies actively developing 180+ pipeline drugs, spanning various disease areas and therapeutic approaches. • Recent clinical advances include promising results from MaaT Pharma's Phase 3 ARES study for GI-aGvHD and Vedanta Biosciences' Phase 2 CONSORTIUM study of VE303 for recurrent C. difficile infection. • Multiple innovative approaches are being pursued, including live biotherapeutic products, with companies like Microbiotica's MB097 showing potential in enhancing immunotherapy responses in cancer treatment.

Follicular Lymphoma Pipeline Shows Promise with Over 55 Therapies in Development

• The follicular lymphoma treatment landscape is evolving, with over 55 therapies in development by more than 50 active pharmaceutical companies. • Key players like Incyte, AstraZeneca, and Johnson & Johnson are evaluating novel drugs, including CAR-T therapies and targeted agents, to improve patient outcomes. • Tafasitamab is expected to have a supplemental Biologics License Application filed in August 2024 for patients who have failed prior therapies. • Emerging therapies in the pipeline include TQ-B3525, NKTR-255, and Zilovertamab vedotin, targeting various mechanisms to combat follicular lymphoma.
© Copyright 2025. All Rights Reserved by MedPath