MedPath

Dequalinium

Generic Name
Dequalinium
Drug Type
Small Molecule
Chemical Formula
C30H40N4
CAS Number
6707-58-0
Unique Ingredient Identifier
E7QC7V26B8

Overview

Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation. It is also used in vaginal tablets to treat bacterial vaginosis.

Background

Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation. It is also used in vaginal tablets to treat bacterial vaginosis.

Indication

Dequalinium is used in several OTC products to treat mouth infections and inflammation, such as tonsillitis, pharyngitis, and gingivitis. As vaginal tablets, dequalinium is indicated for the treatment of bacterial vaginosis in adult women under 55 years of age.

Associated Conditions

  • Bacterial Vaginosis (BV)
  • Gingivitis
  • Inflammation of Mouth
  • Oral Candidiasis
  • Oral Malodor (Halitosis)
  • Oral bacterial infection
  • Pharyngitis
  • Stomatitis
  • Tonsillitis
  • Oral infections
  • Throat infections
  • Throat inflammation
  • Tongue inflammation
  • Ulceration of the mouth

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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