Tolcapone
- Generic Name
- Tolcapone
- Brand Names
- Tasmar
- Drug Type
- Small Molecule
- Chemical Formula
- C14H11NO5
- CAS Number
- 134308-13-7
- Unique Ingredient Identifier
- CIF6334OLY
Overview
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Background
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Indication
Used as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies.
Associated Conditions
- Idiopathic Parkinson's Disease
Clinical Trials
FDA Approved Products
Singapore Approved Products
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