Unknown Manufacturer
Pegvaliase is an enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment.
Pegvaliase is an enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment.
Pegvaliase is a phenylalanine ammonia lyase (PAL) enzyme that temporarily restores the levels of deficient enzyme and reduces blood phenylalanine concentrations by converting phenylalanine to ammonia and trans-cinnamic acid . Formed conversion products are metabolized in the liver and later excreted in the urine .
用于尽管接受先前可用的治疗方案但仍无法充分控制血液苯丙氨酸（Phe）水平（血液Phe水平＞600微摩尔/升）的16岁及以上苯丙酮尿症（罕见病：PKU）患者，降低其血液Phe水平 。
1 associated conditions
One entry per invention. Patent families filed in the US, EP, WO and CN offices.
No patents found under this name
Patent documents usually refer to a drug by its chemical name or development code rather than its generic name, and applications are only published about 18 months after filing — so a newer drug may not appear here yet.
