Tislelizumab

Generic Name
Tislelizumab
Brand Names
Tevimbra, Tizveni
Drug Type
Biotech
Chemical Formula
-
CAS Number
1858168-59-8
Unique Ingredient Identifier
0KVO411B3N
Background

Tislelizumab is under investigation in clinical trial NCT02660034 (The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Subjects With Advanced Solid Tumors).

Indication

⑴用于治疗至少经过二线系统化疗的复发或难治性经典型霍奇金淋巴瘤(R/R cHL)患者。

⑵用于治疗局部晚期或转移性尿路上皮癌。

⑶联合化疗用于治疗一线晚期非鳞状非小细胞肺癌(NSCLC)患者。

⑷用于治疗既往接受过治疗的不可切除肝细胞癌患者。

⑸用于治疗晚期恶性实体瘤

Associated Conditions
-
Associated Therapies
-

Tislelizumab Combined With Neoadjuvant Chemotherapy Used in the Perioperative Treatment.

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-19
Last Posted Date
2024-04-19
Lead Sponsor
Xiangdong Cheng
Target Recruit Count
134
Registration Number
NCT06374901
Locations
🇨🇳

Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, China

Tislelizumab in Combination With Chemotherapy as a Neoadjuvant Treatment for Advanced Endometrial Cancer

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-12
Last Posted Date
2024-04-12
Lead Sponsor
Zhongnan Hospital
Target Recruit Count
20
Registration Number
NCT06363708
Locations
🇨🇳

The Central Hospital of Wuhan, Wuhan, Hubei, China

🇨🇳

Hubei maternal and child health care hospital, Wuhan, Hubei, China

🇨🇳

Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China

Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer

First Posted Date
2024-04-10
Last Posted Date
2024-04-10
Lead Sponsor
The Affiliated Hospital of Qingdao University
Target Recruit Count
30
Registration Number
NCT06357598
Locations
🇨🇳

the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China

TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.

First Posted Date
2024-04-09
Last Posted Date
2024-08-09
Lead Sponsor
Jiangsu Healthy Life Innovation Medical Technology Co., Ltd
Target Recruit Count
30
Registration Number
NCT06353360
Locations
🇨🇳

Huashan Hospital affiliated to Fudan University, Shanghai, China

Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors

First Posted Date
2024-04-05
Last Posted Date
2024-08-26
Lead Sponsor
Sichuan University
Target Recruit Count
9
Registration Number
NCT06349837
Locations
🇨🇳

West China Hospital, Sichuan University, Chengdu, Sichuan, China

A Phase II Multicenter Clinical Study of Improved Short-course Radiotherapy Combined With CAPOX and PD-1 Monoclonal Antibody for Locally Advanced Mid-low Rectal Cancer

First Posted Date
2024-03-27
Last Posted Date
2024-07-15
Lead Sponsor
Fujian Cancer Hospital
Target Recruit Count
31
Registration Number
NCT06333769
Locations
🇨🇳

Fujian Cancer Hospital, Fuzhou, Fujian, China

HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma

First Posted Date
2024-03-27
Last Posted Date
2024-10-15
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
300
Registration Number
NCT06333561
Locations
🇨🇳

Chinese PLA General hospital, Beijing, Beijing, China

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