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TA-CIN

Generic Name
TA-CIN
Drug Type
Biotech
Background

TA-CIN is a subunit vaccine comprising L2/E6/E7 proteins from Human Papillomavirus (HPV16), designed to generate a strong cellular immune response against HPV-infected cells.

Indication

Investigated for use/treatment in cervical dysplasia/cancer.

TA-CIN Vaccine With Anti-PD-1 Therapy in Recurrent HPV16-associated Cancers

Phase 1
Withdrawn
Conditions
Recurrent Human Papillomavirus Type 16 Associated Cancer
Interventions
First Posted Date
2021-11-24
Last Posted Date
2022-12-01
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Registration Number
NCT05132803
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Women & Infants Center, University of Alabama at Birmingham, Birmingham, Alabama, United States

Study of Treatment for HPV16+ ASC-US or LSIL

Phase 1
Recruiting
Conditions
LSIL
ASC-US
Interventions
First Posted Date
2019-04-12
Last Posted Date
2025-01-30
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
30
Registration Number
NCT03913117
Locations
🇺🇸

UAB | The University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

Phase 1
Completed
Conditions
HPV16 Associated Cervical Cancer
Interventions
First Posted Date
2015-04-01
Last Posted Date
2025-03-04
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
14
Registration Number
NCT02405221
Locations
🇺🇸

Women & Infants Center, University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

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