Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia

Not Applicable

Completed

Conditions: Orthopedic Disorders
Foot Diseases
Injuries, Foot
Injuries, Knee
Injuries, Leg

Interventions: Procedure: Perineural Injection for Subgluteal Sciatic Nerve Block
Procedure: Intraneural Injection for Subgluteal Sciatic Nerve Block
Procedure: Femoral Nerve Block
Procedure: Patient-Controlled Postoperative Analgesia
Drug: Ropivacaine

First Posted Date: 2013-12-03

Last Posted Date: 2013-12-04

Lead Sponsor: University of Parma

Target Recruit Count: 64

Registration Number: NCT01999647

Locations: 🇮🇹
Anesthesia, Critical Care and Pain Medicine - University of Parma, Parma, PR, Italy

Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain

Not Applicable

Terminated

Conditions: Acetabular Labrum Tear
Internal Derangement of Hip

Interventions: Drug: Ropivacaine
Drug: Placebo

First Posted Date: 2013-11-28

Last Posted Date: 2018-10-03

Lead Sponsor: Rush University Medical Center

Target Recruit Count: 3

Registration Number: NCT01997567

Locations: 🇺🇸
Rush Oak Park Hospital, Oak Park, Illinois, United States

USG Brachial Plexus Block for Upper Extremity Surgery

Not Applicable

Completed

Conditions: Rupture of Tendon of Wrist and Hand
Injuries to the Wrist, Hand and Fingers (S60-S69)
Ganglion Cysts
Fracture at Wrist and/or Hand Level
Carpal Tunnel Syndrome

Interventions: Drug: Ropivacaine

First Posted Date: 2013-11-25

Last Posted Date: 2015-07-21

Lead Sponsor: Jens Borglum Neimann

Target Recruit Count: 120

Registration Number: NCT01993290

Locations: 🇩🇰
Department of anaesthesiology, Bispebjerg Hospital, Copenhagen, Denmark

Popliteal Sciatic Nerve Block: Intraneural or Extraneural?

Phase 4

Completed

Conditions: Hallux Valgus

Interventions: Procedure: Intraneural injection
Procedure: Extraneural injection
Drug: Ropivacaine
Device: PAJUNK SonoPlex 22G needle.

First Posted Date: 2013-11-19

Last Posted Date: 2015-02-27

Lead Sponsor: ASST Gaetano Pini-CTO

Target Recruit Count: 88

Registration Number: NCT01987128

Locations: 🇮🇹
Istituto Ortopedico G. Pini, Milan, Milano, Italy

Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery

Phase 1

Terminated

Conditions: Pain

Interventions: Drug: Clonidine
Drug: ropivacaine

First Posted Date: 2013-11-18

Last Posted Date: 2016-11-04

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 14

Registration Number: NCT01986751

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy

Phase 3

Completed

Conditions: Knee Injury

Interventions: Drug: Dexamethasone
Drug: Ropivacaine

First Posted Date: 2013-10-29

Last Posted Date: 2018-12-11

Lead Sponsor: Nationwide Children's Hospital

Target Recruit Count: 77

Registration Number: NCT01971645

Locations: 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States

Blood Levels of Local Anaesthetic in Knee Arthroplasty Using a Continuous Infusion Device

Conditions: Osteoarthritis, Knee

Interventions: Drug: Ropivacaine

First Posted Date: 2013-09-05

Last Posted Date: 2013-09-05

Lead Sponsor: Golden Jubilee National Hospital

Target Recruit Count: 30

Registration Number: NCT01935648

Locations: 🇬🇧
Golden Jubilee National Hospital, Clydebank, West Dunbartonshire, United Kingdom

Adductor Canal Blockade vs Femoral Nerve Blockade on Muscle Strength, Mobility and Pain After TKA

Phase 4

Completed

Conditions: Mobility After Total Knee Arthroplasty

Interventions: Drug: Ropivacaine
Drug: Placebo

First Posted Date: 2013-08-14

Last Posted Date: 2014-01-10

Lead Sponsor: University Hospital, Gentofte, Copenhagen

Target Recruit Count: 50

Registration Number: NCT01922596

Locations: 🇩🇰
Gentofte Hospital, Copenhagen, Denmark

Continuous Preperitoneal Infusion of Ropivacaine After Open Liver Resection: Effect on Post-operative Recovery and Morbidity.

Phase 2

Terminated

Conditions: Hepatic Resection
Laparotomy

Interventions: Drug: wound infusion ropivacaine

First Posted Date: 2013-07-01

Last Posted Date: 2014-06-26

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 5

Registration Number: NCT01890408

Locations: 🇫🇷
Département anesthésie-réanimation, Paris, France

Blood Levels of Local Anaesthetic in Knee Arthroplasty

Completed

Conditions: Arthritis of Knee

Interventions: Drug: Ropivacaine

First Posted Date: 2013-06-10

Last Posted Date: 2013-06-11

Lead Sponsor: Golden Jubilee National Hospital

Target Recruit Count: 20

Registration Number: NCT01873313

Locations: 🇬🇧
Golden Jubilee National Hospital, Clydebank, West Dunbartonshire, United Kingdom

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