Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Blood Levels of Local Anaesthetic in Hip Arthroplasty

Completed

Conditions: Osteoarthritis, Hip

Interventions: Drug: Ropivacaine

First Posted Date: 2013-06-05

Last Posted Date: 2013-06-05

Lead Sponsor: Golden Jubilee National Hospital

Target Recruit Count: 20

Registration Number: NCT01869946

Locations: 🇬🇧
Golden Jubilee National Hospital, Clydebank, West Dunbartonshire, United Kingdom

Continuous Versus Intermittent Sciatic Block for Total Knee Arthroplasty

Phase 4

Completed

Conditions: Total Knee Arthroplasty
Pain

Interventions: Drug: Ropivacaine

First Posted Date: 2013-04-30

Last Posted Date: 2015-03-31

Lead Sponsor: Kreiskrankenhaus Dormagen

Target Recruit Count: 140

Registration Number: NCT01843153

Locations: 🇩🇪
KKH Dormagen, Dormagen, Germany

USG Nerve Blocks for ACL Reconstruction

Not Applicable

Completed

Conditions: Pain, Postoperative

Interventions: Drug: placebo
Drug: Ropivacaine

First Posted Date: 2013-04-26

Last Posted Date: 2014-07-31

Lead Sponsor: Jens Borglum Neimann

Target Recruit Count: 82

Registration Number: NCT01840800

Locations: 🇩🇰
Bispebjerg Hospital, department of anesthesiology, Copenhagen, Denmark

Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters

Phase 2

Completed

Conditions: Obesity
Scheduled Cardiac Surgery
Sternotomy
Elderly Patients
Chronic Bronchitis

Interventions: Drug: placebo
Drug: Ropivacaine

First Posted Date: 2013-04-11

Last Posted Date: 2018-07-05

Lead Sponsor: University Hospital, Clermont-Ferrand

Target Recruit Count: 120

Registration Number: NCT01828788

Locations: 🇫🇷
CHU Clermont-Ferrand, Clermont-Ferrand, France

Ultrasound-guided Abdominal Wall Nerve Blockade in Laparoscopic Surgery for Acute Appendicitis.

Not Applicable

Completed

Conditions: Appendicitis

Interventions: Drug: Saline 9%
Drug: Ropivacaine

First Posted Date: 2013-04-08

Last Posted Date: 2015-07-22

Lead Sponsor: Bispebjerg Hospital

Target Recruit Count: 56

Registration Number: NCT01825863

Locations: 🇩🇰
Department of anaesthesiology, Bispebjerg Hospital, Copenhagen, Denmark

Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery

Not Applicable

Terminated

Conditions: Robotic Assisted Laparoscopic Surgery
Bilateral Dual Transversus Abdominis Plane Block
Pain Treatment

Interventions: Drug: Isotonic potassium chloride
Drug: Ropivacaine

First Posted Date: 2013-01-04

Last Posted Date: 2015-05-12

Lead Sponsor: Aalborg University Hospital

Target Recruit Count: 80

Registration Number: NCT01760161

Locations: 🇩🇰
Aalborg Hospital, Aalborg, Region Nord, Denmark

Continuous Wound Infusion in Lumbar or Thoracic Surgery

Phase 2

Completed

Conditions: Lumbar Spine Surgery
Thoracic Spine Surgery

Interventions: Drug: Ropivacaine
Drug: Saline solution 0.9%

First Posted Date: 2012-12-06

Last Posted Date: 2012-12-06

Lead Sponsor: University Hospital, Grenoble

Target Recruit Count: 60

Registration Number: NCT01743794

Locations: 🇫🇷
University Hospital, Departement of Anesthesia and Intensive Care, Grenoble, Rhone Alpes, France

Pain Treatment After TKA With LIA and Intra-articular Continuous Infusion Pump

Phase 4

Completed

Conditions: Postoperative Pain Management

Interventions: Drug: Placebo
Drug: Ropivacaine

First Posted Date: 2012-11-15

Last Posted Date: 2014-11-26

Lead Sponsor: Region Skane

Target Recruit Count: 200

Registration Number: NCT01726686

Locations: 🇸🇪
Department of Orthopedics, Skane University Hospital, Lund University, Lund, Sweden

Evaluation of Block Duration in Type 2 Diabetes Patients

Phase 4

Completed

Conditions: Diabetes Type 2

Interventions: Drug: ropivacaine

First Posted Date: 2012-10-11

Last Posted Date: 2012-12-24

Lead Sponsor: Pierre and Marie Curie University

Target Recruit Count: 70

Registration Number: NCT01704612

Locations: 🇫🇷
APHP Pitié-Sampetriere, Paris, France

Epidural Analgesia and Troubles of Fetal Cardiaq Rythm : Effect of the Systemic Transfer of Ropivacaine and Sufentanil

Phase 4

Completed

Conditions: Fetal Cardiac Rhythm Abnormalities

Interventions: Drug: ropivacaine

First Posted Date: 2012-09-18

Last Posted Date: 2016-01-25

Lead Sponsor: University Hospital, Rouen

Target Recruit Count: 40

Registration Number: NCT01686347

Locations: 🇫🇷
centre hospitalier universitaire de Rouen, Hopital Charles Nicolle, Rouen, France

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