Diazoxide
- Generic Name
- Diazoxide
- Brand Names
- Proglycem
- Drug Type
- Small Molecule
- Chemical Formula
- C8H7ClN2O2S
- CAS Number
- 364-98-7
- Unique Ingredient Identifier
- O5CB12L4FN
- Background
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels. It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insu...
- Indication
Oral diazoxide is indicated to manage hypoglycemia due to hyperinsulinism associated with conditions such as inoperable islet cell adenoma or carcinoma, and extrapancreatic malignancy in adults, or leucine sensitivity, islet cell hyperplasia, nesidioblastosis, extrapancreatic malignancy, islet cell adenoma, and adenomatosis in infants and children. In infant...
- Associated Conditions
- Hyperinsulinemic Hypoglycemia
- Associated Therapies
- -
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