MedPath

Horse chestnut

Generic Name
Horse chestnut
Drug Type
Biotech
Unique Ingredient Identifier
3C18L6RJAZ

Overview

Horse chestnut is a flowering plant commonly referred to as Aesculus hippocastanum. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are processed to remove the toxic component, resulting in purified horse chestnut seed extract (HCSE) . The active component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and reduces swelling and inflammation of the legs. Its therapeutic potential in the treatment of chronic venous insufficiency is being studied.

Background

Horse chestnut is a flowering plant commonly referred to as Aesculus hippocastanum. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are processed to remove the toxic component, resulting in purified horse chestnut seed extract (HCSE) . The active component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and reduces swelling and inflammation of the legs. Its therapeutic potential in the treatment of chronic venous insufficiency is being studied.

Indication

No indication information available.

Associated Conditions

  • Back Pain Lower Back
  • Back pain
  • Cervical Syndrome
  • Contusions
  • Haemorrhoids
  • Sciatica
  • Thrombophlebitis
  • Trigger Finger Disorder
  • Vessels; Varicose
  • Hematomas

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor

No clinical trials found

No clinical trials found for this drug

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code
ORAL
10 [hp_X] in 59 mL
2025/05/20
57955-2822
ORAL
10 [hp_X] in 59 mL
2025/05/23
57955-6031
ORAL
10 [hp_X] in 59 mL
2025/05/19
57955-6163

EMA Approved Products

Medicine Name
EMA Number
Auth. Holder
Country
Drug Type
Status
Issued
Opinion
Revision

No EMA products found

No EMA products found for this drug

HSA Approved Products

Product Name
Manufacturer
Dosage Form
Strength
Approved
Approval No.

No HSA products found

No HSA products found for this drug

NMPA Approved Products

Product Name
Approval No.
Manufacturer
Dosage Form
Trade Name
Strength
Type
Status
Date
Import

No NMPA products found

No NMPA products found for this drug

PPB Approved Products

Product Name
Registration Code
Company
Category
Sale Type
Reg. Date

No PPB products found

No PPB products found for this drug

TGA Approved Products

Product Name
ARTG ID
Sponsor
Status
Reg. Date
Ingredient
482767
Active
2025/03/17
Aesculus hippocastanum
356123
Active
2021/03/03
Aesculus hippocastanum
398237
Active
2022/10/24
Aesculus hippocastanum
214424
Active
2013/09/11
Aesculus hippocastanum
234772
Active
2015/03/11
Aesculus hippocastanum
393510
Active
2022/08/05
Aesculus hippocastanum
350161
Active
2020/11/30
Aesculus hippocastanum
350160
Active
2020/11/30
Aesculus hippocastanum
356164
Active
2021/03/04
Aesculus hippocastanum
362072
Active
2021/04/15
Aesculus hippocastanum
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