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Bimatoprost

Generic Name
Bimatoprost
Brand Names
Durysta, Latisse, Lumigan, Ganfort
Drug Type
Small Molecule
Chemical Formula
C25H37NO4
CAS Number
155206-00-1
Unique Ingredient Identifier
QXS94885MZ

Overview

Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension and glaucoma. Bimatoprost is also used to treat eyelash hypotrichosis, or sparse eyelash growth. It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug.

Background

Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension and glaucoma. Bimatoprost is also used to treat eyelash hypotrichosis, or sparse eyelash growth. It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug.

Indication

Bimatoprost is used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. These patients must be intolerant to other intraocular pressure lowering medications or inadequately responsive to other treatments. Bimatoprost is also indicated to treat eyelash hypotrichosis.

Associated Conditions

  • Hypotrichosis of the eyelashes
  • Increased Intra Ocular Pressure (IOP)

Clinical Trials

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Title
Posted
Study ID
Phase
Status
Sponsor
2011/12/12
N/A
Completed
2011/11/03
Phase 4
Completed
2011/10/07
Phase 4
Completed
2011/08/31
Phase 3
Terminated
2011/07/12
Phase 3
Completed
2011/07/12
Phase 3
Completed
2011/07/06
Phase 4
Completed
Kenneth Beer
2011/03/29
Phase 2
Completed
2011/03/29
Phase 2
Completed
2011/02/18
Phase 4
Completed

FDA Approved Products

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