Atropine
- Generic Name
- Atropine
- Brand Names
- Atnaa, Atropen, Busulfex, Donnatal, Duodote, Enlon-plus, Isopto Atropine, Lomotil, Minims Atropine Sulphate, Motofen, Phenohytro
- Drug Type
- Small Molecule
- Chemical Formula
- C17H23NO3
- CAS Number
- 51-55-8
- Unique Ingredient Identifier
- 7C0697DR9I
- Background
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine ...
- Indication
The intravenous, intramuscular, subcutaneous, intraosseous and endotracheal use of atropine is indicated for the temporary blockade of severe or life-threatening muscarinic effects. The intramuscular use of atropine in the form of a pen injector is indicated for the treatment of poisoning by susceptible organophosphorus nerve agents having cholinesterase act...
- Associated Conditions
- Amblyopia, Atrioventricular Heart-block, Bradycardia, Bronchospasm, Crying, Detrusor Hyperreflexia, Excessive bronchial secretion, Hypertonic uterine contraction, Hypertonicity of the small intestine, Ocular Inflammation, Parkinsonism, Peptic Ulcer, Poisoning by parasympathomimetics (cholinergics), Poisoning caused by mushrooms, Poisoning caused by organophosphate anticholinesterase nerve agents, Poisoning caused by organophosphorus pesticides, Pylorospasm, Rhinorrhoea, Sinus Bradycardia, Spasms, Toxic effect of organophosphate and carbamate, Hypermobility of the colon, Laughing, Life-threatening muscarinic side effects, Muscarinic side effects, Severe muscarinic side effects
- Associated Therapies
- -
Atropine for Preventing Ventilator-Associated Pneumonia
- First Posted Date
- 2016-03-10
- Last Posted Date
- 2016-03-10
- Lead Sponsor
- Universidade de Passo Fundo
- Target Recruit Count
- 40
- Registration Number
- NCT02704923
Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography
- First Posted Date
- 2016-03-04
- Last Posted Date
- 2016-10-25
- Lead Sponsor
- University of Florence
- Target Recruit Count
- 58
- Registration Number
- NCT02698969
- Locations
- 🇮🇹
Azienda Ospdaliero Universitaria Careggi, Florence, Italy
Effects of Systemic or Adjunct Tramadol Addition to Lidocaine Used for IVRA in Patients Undergoing Hand Surgery
- First Posted Date
- 2016-01-20
- Last Posted Date
- 2016-01-20
- Lead Sponsor
- Bagcilar Training and Research Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02658721
Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic Pathways
- Conditions
- Interventions
- First Posted Date
- 2015-12-17
- Last Posted Date
- 2015-12-17
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 28
- Registration Number
- NCT02633579
Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia
- First Posted Date
- 2015-12-04
- Last Posted Date
- 2016-11-08
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT02622126
- Locations
- 🇪🇬
Faculty of Medicine, Assiut, Egypt
Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2016-01-18
- Lead Sponsor
- Sira Bang
- Target Recruit Count
- 120
- Registration Number
- NCT02522858
- Locations
- 🇰🇷
Inje University Seoul Paik Hospital, Seoul, Korea, Seoul, Jung-Gu,, Korea, Republic of
Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain
- First Posted Date
- 2015-05-15
- Last Posted Date
- 2017-03-09
- Lead Sponsor
- University of Debrecen
- Target Recruit Count
- 3
- Registration Number
- NCT02445599
- Locations
- 🇭🇺
UNIVERSITY OF DEBRECEN FACULTY OF MEDICINE Department of Anesthesiology and Intensive Care, Debrecen, Hajdú-Bihar, Hungary
Effects of Neuromuscular Block Reversal With Sugammadex vs Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery
- Conditions
- Interventions
- First Posted Date
- 2015-02-11
- Last Posted Date
- 2017-02-23
- Lead Sponsor
- Enrique Alday Muñoz
- Target Recruit Count
- 130
- Registration Number
- NCT02361060
- Locations
- 🇪🇸
Hospital Universitario de La Princesa, Madrid, Spain
🇪🇸Anesthesiology Service. Hospital Universitario La Princesa, Madrid, Spain
Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy
- First Posted Date
- 2014-12-31
- Last Posted Date
- 2018-11-30
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 90
- Registration Number
- NCT02327923
- Locations
- 🇳🇵
BP Koirala Institute of Health Sciences, Dharan, Sunsari District, Nepal
Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort
- Conditions
- Interventions
- First Posted Date
- 2014-08-29
- Last Posted Date
- 2014-10-28
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 76
- Registration Number
- NCT02228473
- Locations
- 🇰🇷
Seoul National University of Hospital, Seoul, Korea, Republic of, Korea, Republic of
Drug Development Updates
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